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Oct 15, 2024 | 
broadinstitute.org | Ari Navetta |Ramnik Xavier |Clary B. Clish |Caroline Uhler
Though his focus shifted over time, being a scientist was always the plan for Eric Brown since kindergarten. “First it was dinosaurs and whales, and then it turned into birds, and then it turned into microbes,” he said. Years later, Brown began studying structural biology as an undergraduate student at the University of Guelph in Ontario, Canada.
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Oct 3, 2024 | 
medicalxpress.com | Ari Navetta
This article has been reviewed according to Science X's editorial process and policies . Editors have highlighted the following attributes while ensuring the content's credibility:The largest and most diverse study to date of epilepsy's genetic factors has revealed new potential targets for treatment, both shared by and unique to different subtypes of epilepsy. The findings point to factors involved in how neurons communicate and fire, suggesting potential targets for new therapies.
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Oct 3, 2024 | 
broadinstitute.org | Ari Navetta |Benjamin M. Neale
The largest and most diverse study to date of epilepsy’s genetic factors has revealed new potential targets for treatment, both shared by and unique to different subtypes of epilepsy. The findings point to factors involved in how neurons communicate and fire, suggesting potential targets for new therapies. In the future, the results could also help doctors tailor treatments to a patient’s genome. Epilepsy is one of the most common neurological disorders.
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Sep 23, 2024 | 
phys.org | Ari Navetta
The life-saving use of messenger RNA (mRNA) in COVID-19 vaccines was a public example of the potential of mRNA-based therapies, which hold great promise for a wide range of treatment applications from cancer immunotherapy to gene editing.
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Sep 23, 2024 | 
broadinstitute.org | Ari Navetta |Xiao Wang
The life-saving use of messenger RNA (mRNA) in COVID-19 vaccines was a public example of the potential of mRNA-based therapies, which hold great promise for a wide range of treatment applications from cancer immunotherapy to gene editing.
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Sep 17, 2024 | 
broadinstitute.org | Ari Navetta
A desire to constantly learn more has fueled Edana Martin’s varied career in science. Growing up in Colombia, she became fascinated with physics and astronomy, seeking to understand how the world around her works. Martin studied nuclear physics and completed a PhD at Universidad Nacional de Colombia where she simulated physical interactions between different particles of matter. Along the way, Martin taught herself a wide range of programming and data science skills.
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Sep 5, 2024 | 
phys.org | Ari Navetta
When Steve Carr, senior director of the Proteomics Platform at the Broad Institute of MIT and Harvard, began working in proteomics, the field was able to detect only the most abundant proteins in a given sample. In recent years, increasingly sensitive mass spectrometers have paved the way for enormous progress: scientists are now able to detect and analyze nearly all proteins expressed in a sample, including ones present only in miniscule amounts.
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Jul 12, 2024 | 
medicalxpress.com | Ari Navetta
A number of cancers, including certain brain and liver tumors, as well as myeloid leukemias, are driven by mutations in the enzyme isocitrate dehydrogenase 1, or IDH1. Drugs that block mutated IDH1 (mIDH1) have recently come onto the market and effectively slow tumor growth, but the exact mechanism at work to stall tumors is still unclear.
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Jul 11, 2024 | 
broadinstitute.org | Ari Navetta |Robert T. Manguso
A number of cancers, including certain brain and liver tumors, as well as myeloid leukemias, are driven by mutations in the enzyme isocitrate dehydrogenase 1, or IDH1. Drugs that block mutated IDH1 (mIDH1) have recently come onto the market and effectively slow tumor growth, but the exact mechanism at work to stall tumors is still unclear.
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Aug 9, 2023 | 
cspinet.org | Ari Navetta
Plenty of veg, filling whole grains, and plant-based proteins. Whether you’re meatless on Mondays or going all-in, look no further than these vegetarian main dish salads for your dinner plans this week. Whether you choose to go plant-based for health, environmental, or ethical reasons, it can be tricky to create filling meals as a vegetarian newcomer. Luckily, it’s not as hard as it seems.
