Xiao Wang

2 weeks ago | pubs.acs.org | Xiao Wang |Jing-Yuan Ma |Mingze Lu |Wei Du

Biological and Medical Applications of Materials and InterfacesJune 12, 2025Xiao WangState Key Laboratory of Digital Medical Engineering, Jiangsu Key Laboratory for Biomaterials and Devices, School of Biological Science and Medical Engineering & Basic Medicine Research and Innovation Center of Ministry of Education, Southeast University, Nanjing 211102, P. R.

2 weeks ago | dx.doi.org | Xiao Wang |Jing-Yuan Ma |Mingze Lu |Wei Du

Biological and Medical Applications of Materials and InterfacesJune 12, 2025Xiao WangState Key Laboratory of Digital Medical Engineering, Jiangsu Key Laboratory for Biomaterials and Devices, School of Biological Science and Medical Engineering & Basic Medicine Research and Innovation Center of Ministry of Education, Southeast University, Nanjing 211102, P. R.

1 month ago | tandfonline.com | Zhou Chen |Xiao Wang |Xinan Zhang |Ming Lin

ABSTRACTLarge Language Models (LLMs) have demonstrated a remarkable capacity to efficiently learn, comprehend, and process extensive datasets and academic literature, leading to their widespread application across a variety of disciplines. However, the adoption of LLMs in geoscience remains constrained by several inherent limitations, including a lack of geoscience knowledge, difficulties in updating information, insufficient autonomy, high operational costs, and low efficiency.

1 month ago | nature.com | Shengsong Xu |Xiao Wang |Jinyi Xu |Xingyu Lei |MengYi Wang |Xiao Yang | +3 more

To investigate the causal relationship between depression, anxiety, and myopia. The multivariable Mendelian randomization (MR) design using summary statistics from independent genome-wide association studies (GWAS) was employed. The anxiety and depression, were used as exposures, and myopia was used as the outcome. Genetic variants associated with depression were derived using GWAS summary statistics from the FinnGen consortium database. Genetic variants associated with anxiety were derived from the Psychiatric Genomics consortium. The inverse-variance-weighted method was the main applied analytic tool and was complemented with comprehensive sensitivity analyses. A total of 21, 10 SNPs were selected as instrumental variables for depression and anxiety, respectively. Based on the IVW analysis, both depression (OR = 1.010, 95% CI = 1.002–1.018, P = 0.016) and anxiety (OR = 1.083, 95%CI = 1.022–1.149, P = 0.008) increased the risk of myopia. After adjusting in the multivariable MR, the IVW and Egger methods indicated that depression (OR = 1.004, 95%CI = 1.000–1.008, P = 0.030) or anxiety (OR = 1.004, 95%CI = 1.001–1.008, P = 0.026) was still associated with elevated risks of myopia. The current study identified a causal relationship between anxiety, depression, and an increased risk of myopia. These observations suggest that when developing strategies to control myopia, it is also important to focus on the mental health of children. Further detailed research is needed to fully understand this issue.

2 months ago | arxiv.org | Xiao Wang |Bo Jiang |Lin Zhu |Guoqi Li

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