Aroon Hingorani

2 weeks ago | freerepublic.com | Rachel Jordan |Aroon Hingorani |Nicholas Wald

Free RepublicBrowse · SearchGeneral/ChatTopics · Post ArticleSkip to comments. Could This Revolutionary “Polypill” Be the Key to Preventing Heart Disease? [UK]Scitech Daily ^ | March 11, 2025 | University College LondonPosted on by Red BadgerAcademics from UCL propose a national polypill program for everyone over 50 in the UK, combining a statin and three blood pressure drugs, to prevent thousands of heart attacks and strokes annually.

1 month ago | bmj.com | Rachel Jordan |Aroon Hingorani |Nicholas Wald

Rachel E. Jordan, professor of epidemiology and primary care1, Aroon D. Hingorani, professor of genetic epidemiology2, Nicholas J. Wald, professor of preventive medicine21University of Birmingham2University College LondonHeart attacks and strokes rise exponentially with age and make a major contribution to increasing healthcare costs and lost productivity. In the UK more than 7 million people are living with cardiovascular disease.

Sep 28, 2023 | nature.com | Maryam Kavousi |Haojie Lu |Chani J. Hodonsky |Joris Deelen |Xiuqing Guo |Leo-Pekka Lyytikäinen | +31 more

AbstractCoronary artery calcification (CAC), a measure of subclinical atherosclerosis, predicts future symptomatic coronary artery disease (CAD). Identifying genetic risk factors for CAC may point to new therapeutic avenues for prevention. Currently, there are only four known risk loci for CAC identified from genome-wide association studies (GWAS) in the general population.

Jul 18, 2023 | nature.com | Claudia Langenberg |Aroon Hingorani

AbstractGlobally, the number of people with multiple co-occurring diseases will increase substantially over the coming decades, with important consequences for patients, carers, healthcare systems and society. Addressing this challenge requires a shift in the prevailing clinical, educational and scientific thinking and organization—with a strong emphasis on the maintenance of generalist skills to balance the specialization trends of medical education and research.

May 29, 2023 | nature.com | David Adlam |Takiy-Eddine Berrandou |Adrien Georges |Christopher Nelson |Chris Finan |Siiri E. Iismaa | +21 more

AbstractSpontaneous coronary artery dissection (SCAD) is an understudied cause of myocardial infarction primarily affecting women. It is not known to what extent SCAD is genetically distinct from other cardiovascular diseases, including atherosclerotic coronary artery disease (CAD). Here we present a genome-wide association meta-analysis (1,917 cases and 9,292 controls) identifying 16 risk loci for SCAD.