Benedikt B. Kaufer

Jun 22, 2023 | nature.com | Agnieszka Rybak-Wolf |Emanuel Wyler |Ivano Legnini |Seung Joon Kim |Benedikt B. Kaufer |Andrew Woehler | +2 more

Study designIn this study, we used human cerebral organoids as a model for acute HSV-1. The aim of the study was as follows: (1) to assess cellular and molecular signatures associated with viral infection; (2) to study the outcome of the current antiviral therapy used in clinical practice (ACV); (3) to identify and test better potential therapeutic approaches based on the results of 1 and 2.