Bhoktear Khan

Jan 10, 2025 | science.org | Daniel Rabe |Matthew Weller |Bhoktear Khan |Ahmed Gad |Jessica Morris |Lea Godret-Miertschin | +10 more

AbstractChimeric antigen receptor T cells (CART) targeting CD19 through CD28.ζ signaling induce rapid lysis of leukemic blasts, contrasting with persistent tumor control exhibited by 4-1BB.ζ-CART. We reasoned that molecular dynamics at the CART immune synapse (CARIS) could explain differences in their tumor rejection kinetics.

Jan 10, 2025 | science.org | Daniel Rabe |Matthew Weller |Bhoktear Khan |Juan Zhang

AbstractProtein translation is crucial for fear extinction, a process vital for adaptive behavior and mental health, yet the underlying cell-specific mechanisms remain elusive. Using a Tet-On 3G genetic approach, we achieved precise temporal control over protein translation in the infralimbic medial prefrontal cortex (IL) during fear extinction.

Jan 10, 2025 | science.org | Daniel Rabe |Matthew Weller |Bhoktear Khan |Jing Zhou

AbstractCombining physics with computational models is increasingly recognized for enhancing the performance and energy efficiency in neural networks. Physical reservoir computing uses material dynamics of physical substrates for temporal data processing. Despite the ease of training, building an efficient reservoir remains challenging. Here, we explore beyond the conventional delay-based reservoirs by exploiting the spatiotemporal transformation in all-electric spintronic devices.

Jan 10, 2025 | science.org | Daniel Rabe |Matthew Weller |Bhoktear Khan |TAO WANG

AbstractPerovskite oxides have a wide variety of physical properties that make them promising candidates for versatile technological applications including nonvolatile memory and logic devices. Chemical tuning of those properties has been achieved, to the greatest extent, by cation-site substitution, while anion substitution is much less explored due to the difficulty in synthesizing high-quality, mixed-anion compounds.

Jan 10, 2025 | science.org | Daniel Rabe |Matthew Weller |Bhoktear Khan |Nikolai Kuznetsov

AbstractMagnonics, which harnesses the unique properties of spin waves, offers promising advancements in data processing due to its broad frequency range, nonlinear dynamics, and scalability for on-chip integration. Effective information encoding in magnonic systems requires precise spatial and temporal control of spin waves. Here, we demonstrate the rapid optical control of spin-wave transport in hybrid magnonic-plasmonic structures.