Bin Zheng

Nov 1, 2024 | nature.com | Bin Zheng

AbstractThe mechanical deformation of coals occurring extensively during the geological period (tectonically deformed coals) can directly alter their pore structures and then the storage of coalbed methane. This study in-situ investigated the effects of different mechanical deformations on the ultramicropore structure and the methane adsorption of coal molecules using molecular simulations.

Oct 16, 2024 | nature.com | Bin Zheng |Bowen Li

AbstractAs a transdermal drug delivery method, microneedles offer minimal invasiveness, painlessness, and precise in-situ treatment. However, current microneedles rely on passive diffusion, leading to uncontrollable drug penetration. To overcome this, we developed a pneumatic microneedle patch that uses live Enterobacter aerogenes as microengines to actively control drug delivery.

Jun 11, 2024 | nature.com | Yang Chen |Xingwu Jiang |Jinfeng Wu |Bin Zheng |Dayong Jin

AbstractTo fulfil the demands of rapid proliferation, tumour cells undergo significant metabolic alterations. Suppression of hyperactivated metabolism has been proven to counteract tumour growth. However, whether the reactivation of downregulated metabolic pathways has therapeutic effects remains unexplored. Here we report a nutrient-based metabolic reactivation strategy for effective melanoma treatment.

Nov 28, 2023 | onlinelibrary.wiley.com | Zhenghong Liu |Li Sun |Bin Zheng |Heng Wang

1 INTRODUCTION Bladder cancer (BCa) is the ninth most common malignancy worldwide.1 Every year approximately 573,000 new cases are diagnosed, and more than 213,000 patients die of BCa globally.2 The BCa incidence increases with age, and it is strongly associated with male gender, with men four times more frequently affected than women.3 The main risk factors for BC are tobacco smoking and occupational exposure.4 In terms of pathological types, urothelial carcinoma is dominant in North America...

Nov 3, 2023 | mdpi.com | Chen Guo |Shuai Xu |Bin Zheng |Haiying Liu

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