Articles
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Nov 13, 2024 |
pubs.acs.org | Bo Zhu |Hui Chen |Liwen Shi |Xuefeng Liu
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Sep 23, 2024 |
preprints.org | Chen Huang |Xingyu Chen |Zihan Wang |Bo Zhu
Preprint Article Version 1 This version is not peer-reviewed Version 1 : Received: 23 September 2024 / Approved: 23 September 2024 / Online: 23 September 2024 (15:26:34 CEST) Huang, C.; Chen, X.; Wang, Z.; Zhu, B.; Deng, M.; Qiu, J.; Feng, Y.; Ding, N. Metabolic Reprogramming Induced by Aging Modifies the Tumor Microenvironment. Preprints 2024, 2024091807. https://doi.org/10.20944/preprints202409.1807.v1 Huang, C.; Chen, X.; Wang, Z.; Zhu, B.; Deng, M.; Qiu, J.; Feng, Y.; Ding, N.
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Sep 3, 2024 |
biorxiv.org | Yao Lu |Hao Wu |Bo Zhu |Qianman Peng
AbstractBackground: Protein-tyrosine-phosphatase CD45 is exclusively expressed in all nucleated cells of the hematopoietic system but is rarely expressed in endothelial cells. Interestingly, our recent study indicated that activation of the endogenous CD45 promoter in human endothelial colony forming cells (ECFCs) induced expression of multiple EndoMT marker genes.
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Aug 27, 2024 |
biorxiv.org | Bo Zhu |Krishan Lal Gupta |Kui Cui |Beibei Wang
AbstractRationale: Low density cholesterol receptor (LDLR) in the liver is critical for the clearance of low-density lipoprotein cholesterol (LDL-C) in the blood. In atherogenic conditions, proprotein convertase subtilisin/kexin 9 (PCSK9) secreted by the liver, in a nonenzymatic fashion, binds to LDLR on the surface of hepatocytes, preventing its recycling and enhancing its degradation in lysosomes, resulting in reduced LDL-C clearance.
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Jul 30, 2024 |
biorxiv.org | Beibei Wang |Kui Cui |Bo Zhu |Yunzhou Dong
AbstractSmooth muscle cells in major arteries play a crucial role in regulating coronary artery disease. Conversion of smooth muscle cells into other adverse cell types in the artery propels the pathogenesis of the disease. Curtailing artery plaque buildup by modulating smooth muscle cell reprograming presents us a new opportunity to thwart coronary artery disease.
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