Brittany A. Petros

Oct 11, 2024 | nature.com | Sreekar Mantena |Brittany A. Petros |Cameron Myhrvold |Pardis Sabeti

AbstractCRISPR guide RNA sequences deriving exactly from natural sequences may not perform optimally in every application. Here we implement and evaluate algorithms for designing maximally fit, artificial CRISPR–Cas13a guides with multiple mismatches to natural sequences that are tailored for diagnostic applications.

Feb 6, 2024 | medrxiv.org | Brittany A. Petros |Carly E. Milliren |Pardis Sabeti |Al Ozonoff

PCS is a co-founder of, shareholder in, and advisor to Sherlock Biosciences, Inc.; a board member of and shareholder in the Danaher Corporation; a co-founder of and shareholder in Delve Bio; and a shareholder in NextGenJane and TruGenomix.