Carmelo Gurnari

Nov 14, 2024 | onlinelibrary.wiley.com | Carmelo Gurnari |Valeria Visconte

In their paper, Li et al.1 embarked in the understanding of the determinants of evolution to myelodysplastic syndrome (MDS) and acute myeloid leukaemia (AML) in patients with aplastic anaemia (AA) and paroxysmal nocturnal haemoglobinuria. The authors specifically focused on patients undergoing allogeneic haematopoietic cell transplant (allo-HCT) to study outcomes and differences with patients with AA receiving transplant upfront before progressing to MDS/secondary AML (sAML).

Jul 29, 2024 | nature.com | Fauzia Ullah |Danai Dima |Hetty Carraway |Chao-Yie Yang |Carmelo Gurnari |Valeria Visconte | +1 more

TO THE EDITOR:FMS-like receptor tyrosine kinase 3 (FLT3) expression is almost exclusively found in the myeloid compartment [1]. The FLT3 protein consists of an extracellular region containing the ligand-binding site, a transmembrane domain, a cytoplasmic juxtamembrane domain, and a tyrosine kinase domain (TKD).

Mar 20, 2023 | jacionline.org | Alessandro Bruno |Vita-Salute San Raffaele |Carmelo Gurnari

This year’s best in hematology diagnosis: a new disease is discovered. Hematologist. 2022; 19Beck D.B. Ferrada M.A. Sikora K.A. Ombrello A.K. Collins J.C. Pei W. et al. Somatic mutations in UBA1 and severe adult-onset autoinflammatory disease. N Engl J Med. 2020; 383: 2628-2638Barba T. Jamilloux Y. Durel C.A. Bourbon E. Mestrallet F. Sujobert P. et al. VEXAS syndrome in a woman. Rheumatology (Oxford). 2021; 60: E402-E403Tsuchida N. Kunishita Y. Uchiyama Y. Kirino Y. Enaka M. Yamaguchi Y. et al.