Hetty Carraway

Nov 21, 2024 | nature.com | Carlos Bravo-Pérez |Yasuo Kubota |Simona Pagliuca |Danai Dima |Hetty Carraway |Valeria Visconte

AbstractPast studies described occasional patients with myeloid neoplasms (MN) and coexistent large granular lymphocytic leukemia (LGLL) or T-cell clonopathy of unknown significance (TCUS), which may represent expansion of myeloid clonal hematopoiesis (CH) as triggers or targets of clonal cytotoxic T cell reactions. We retrospectively analyzed 349 LGLL/TCUS patients, 672 MN patients, and 1443 CH individuals to establish the incidence, genetic landscape, and clinical phenotypes of CH in LGLL.

Jul 29, 2024 | nature.com | Fauzia Ullah |Danai Dima |Hetty Carraway |Chao-Yie Yang |Carmelo Gurnari |Valeria Visconte | +1 more

TO THE EDITOR:FMS-like receptor tyrosine kinase 3 (FLT3) expression is almost exclusively found in the myeloid compartment [1]. The FLT3 protein consists of an extracellular region containing the ligand-binding site, a transmembrane domain, a cytoplasmic juxtamembrane domain, and a tyrosine kinase domain (TKD).

Jul 17, 2024 | nature.com | Tariq Kewan |Olisaemeka Ogbue |Sudipto Mukherjee |Anjali Advani |James Cook |Hetty Carraway | +2 more

TO THE EDITOR:Extramedullary deposits of acute myeloid leukemia (eAML), constitute an unusual presentation or complication of AML, which can occur in isolation (isolated eAML) or in the context of a fully-blown leukemic process (synchronous eAML) either at diagnosis or relapse [1,2,3].

Jun 6, 2024 | onclive.com | Hetty Carraway

CommentaryVideoJune 6, 2024Supplements and Featured PublicationsNovel Emerging Therapies in Relapsed/Refractory AMLAuthor(s):Hetty E. Carraway, MD, MBA, discusses current treatment strategies available for patients with acute myeloid leukemia. Hetty E.

May 29, 2024 | onclive.com | Hetty Carraway

Hetty E.