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Nov 24, 2024 | 
link.springer.com | Chang Gung College |Taipei City
AbstractOBI-858 is a brand-new botulinum Type A complex toxin with a specific molecular weight of 760 kDa intended for development for both aesthetic and therapeutic applications. This is a phase I, dose-escalation study to evaluate the safety and preliminary efficacy of OBI-858 in subjects with moderate to severe glabellar lines. Each subject received OBI-858 by intramuscular injections with an assigned dose (10 U, 20 U, and 30 U).
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Nov 10, 2024 | 
bmccancer.biomedcentral.com | Chang Gung College
The flowchart depicted in Fig. 1 delineates the enrollment procedure and patient figures at Kaohsiung Chang Gung Memorial Hospital spanning the years 2015 to 2021. Initially, a total of 601 patients diagnosed with ovarian cancers were enrolled in the investigation. Patients with non-epithelial ovarian cancers, double cancers, or those lacking consistent follow-up were excluded from the analysis.
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Oct 27, 2024 | 
bmccancer.biomedcentral.com | Chang Gung College |Chang Gung
Cancer Registry Annual Report 1972–2022. Taipei City: Health Promotion Administration, Ministry of Health and Welfare, Taiwan; 2020. Lordick F, Carneiro F, Cascinu S, Fleitas T, Haustermans K, Piessen G, et al. Gastric cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up. Ann Oncol. 2022;33(10):1005–20. Article PubMed Google Scholar Shitara K, Fleitas T, Kawakami H, Curigliano G, Narita Y, Wang F, et al.
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Aug 22, 2024 | 
respiratory-research.biomedcentral.com | Chang Gung College |New Taipei |Chang Gung
SRM-1648a, ambient urban particulate matter, was purchased from the National Institute of Standards and Technology (NIST) in US and used in this study. These particles consist of fine and ultrafine particles with an aerodynamic diameter ranging from 1.35 to 30.1 μm (mean 5.85 μm) and are comprised of various polycyclic aromatic hydrocarbons (PAHs) and inorganic and organic elements such as iron, calcium and zinc.
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Jul 24, 2024 | 
link.springer.com | Chang Gung College |Academia Sinica
AbstractNordalbergin is a coumarin extracted from Dalbergia sissoo DC. To date, the biological effects of nordalbergin have not been well investigated. To investigate the anti-inflammatory responses and the anti-oxidant abilities of nordalbergin using lipopolysaccharide (LPS)-activated macrophages and LPS-induced sepsis mouse model.
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Jul 11, 2024 | 
bmccancer.biomedcentral.com | Chang Gung College |Chang Gung
ReferencesJoensuu H, Hohenberger P, Corless C. Gastrointestinal stromal tumour. Lancet. 2013;382:973–83. Article CAS PubMed Google Scholar Heinrich MC, Griffith DJ, Druker BJ, Wait CL, Ott KA, Zigler AJ. Inhibition of c-kit receptor tyrosine kinase activity by STI 571, a selective tyrosine kinase inhibitor. Blood. 2000;96:925–32. Article CAS PubMed Google Scholar Joensuu H, Roberts PJ, Sarlomo-Rikala M, Andersson LC, Tervahartiala P, Tuveson D, et al.
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Apr 22, 2024 | 
jbiomedsci.biomedcentral.com | Li Yu |Chang Gung College |Jan Wu |Keng Poo
Patients for this study were recruited primarily from Chang Gung Memorial Hospital's Rheumatology Clinics. Rheumatologists who confirmed SLE in all examined patients based on American College of Rheumatology criteria [15, 16]. Specific phenotypes of SLE were correlated with biological data. Ninety one patients with SLE (age, 23–80 years; 49.9 ± 11.7 median years) and 27 Health Controls (HCs) (age, 27–52 years; 36.3 ± 5.7 years) were enrolled.
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Apr 3, 2024 | 
virologyj.biomedcentral.com | Chang Gung College
This retrospective study enrolled 144 HBeAg-negative patients without cirrhosis who underwent entecavir treatment between 2012 and 2017 and 83 HBeAg-negative patients without cirrhosis who underwent TAF treatment between 2019 and 2022; for these patients the entecavir or TAF were administrated for antiviral prophylaxis before anticancer management for oncologic and hematologic malignancies, and clinical posttreatment follow-up was conducted for > 6 months.
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Mar 24, 2024 | 
bmcpediatr.biomedcentral.com | Chang Gung |Chang Gung College
Amidst the COVID-19 pandemic, the influx of patients to our emergency department experienced a significant surge towards the close of April 2022, concomitant with an upswing in SARSCoV-2 infections. This pattern underwent a reversal subsequent to the implementation of immunization using the Moderna and BNT vaccines for children (Supplementary Fig. 1).
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Mar 23, 2024 | 
respiratory-research.biomedcentral.com | Chang Gung College |Hong Kong Baptist
DEHP is a widely utilized plasticizer in plastic products. Research indicated that exposure to DEHP might have influenced asthma heterogeneity and associated comorbidities. To address this concern, our aim was to examine variations in DEHP exposure among different asthma phenotypes and comorbidities, utilizing primary and secondary DEHP metabolites. This investigation included the integration of a panel of physiological biomarkers to explore these associations.
