Chaya Moskowitz

Oct 28, 2024 | nature.com | Whitney P. Underwood |Meghan Michalski |Catherine Lee |Gina A. Fickera |Stefan E. Eng |Lydia Y. Liu | +14 more

We developed and evaluated the Digital Platform for Exercise (DPEx): a decentralized, patient-centric approach designed to enhance all aspects of clinical investigation of exercise therapy. DPEx integrated provision of a treadmill with telemedicine and remote biospecimen collection permitting all study procedures to be conducted in patient’s homes. Linked health biodevices enabled high-resolution monitoring of lifestyle and physiological response. Here we describe the rationale and development of DPEx as well as feasibility evaluation in three different cohorts of patients with cancer: a phase 0a development study among three women with post-treatment primary breast cancer; a phase 0b proof-of-concept trial of neoadjuvant exercise therapy in 13 patients with untreated solid tumors; and a phase 1a level-finding trial of neoadjuvant exercise therapy in 53 men with localized prostate cancer. Collectively, our study demonstrates the utility of a fully digital, decentralized approach to conduct clinical trials of exercise therapy in a clinical population.

Sep 19, 2024 | jamanetwork.com | Lee Jones |Chaya Moskowitz |Catherine Lee |Gina A. Fickera

Error in Abstract Neoadjuvant Exercise Therapy in Prostate Cancer Lee W. Jones, PhD; Chaya S. Moskowitz, PhD; Catherine P. Lee, BS, MPH; Gina A. Fickera, BA; Su S. Chun, BA; Meghan G. Michalski, MS; Kurtis Stoeckel, MS; Whitney P. Underwood, BSc; Jessica A. Lavery, MS; Umeshkumar Bhanot, MD, PhD; Irina Linkov, PhD; Chau T. Dang, MD; Behfar Ehdaie, MD; Vincent P. Laudone, MD; James A. Eastham, MD; Anne Collins, RN; Patricia T. Sheerin, RN; Lydia Y. Liu, PhD; Stefan E. Eng, MS; Paul C.

May 22, 2024 | onlinelibrary.wiley.com | Emily S. Tonorezos |Joanne F. Chou |Chaya Moskowitz |Wendy M. Leisenring

CONFLICT OF INTEREST STATEMENT The authors declare no conflicts of interest. REFERENCES 1, , , et al. Survivors of childhood cancer in the United States: prevalence and burden of morbidity. Cancer Epidemiol Biomarkers Prev. 2015; 24(4): 653-663. doi:10.1158/1055-9965.Epi-14-1418 2, . Survivors of childhood and adolescent cancer: life-long risks and responsibilities. Nat Rev Cancer. 2014; 14(1): 61-70. doi:10.1038/nrc3634 3, , , et al.

May 9, 2024 | kosher.com | Chaya Moskowitz

Cauliflowerpepper, to taste1/3 cup flour (can use gluten-free flour)Sauce1 tablespoon garlic powder1 to 2 teaspoons honey (optional, for a sweeter sauce)1. Preheat oven to 375 degrees Fahrenheit. 2. Place cauliflower in a large Ziploc bag. Add oil, salt and pepper and shake to coat. Add flour and shake again. 3. Spread coated cauliflower on a metal baking sheet and spray with cooking spray. 4. Roast cauliflower for 40 minutes. 5.

May 9, 2024 | kosher.com | Chaya Moskowitz

Marinade1 and 1/2 teaspoons hot saucesaltpepper, to tasteChicken1 package baby chicken/pargiyot (boneless chicken bottoms), about 1 and 1/2 pounds1. Combine all marinade ingredients in a Ziploc bag. Place baby chicken in the bag and marinate for at least 20 minutes in the fridge. 2. Grill on an outdoor grill or grill pan on high for four to five minutes per side until cooked through. Tips:These can also be baked in the oven.