Claire Walsh

May 21, 2024 | onlinelibrary.wiley.com | Paul Sweeney |Claire Walsh |Simon Walker-Samuel |Rebecca Shipley

1 INTRODUCTION The microcirculation is a hierarchical structure of blood vessels consisting of arterioles, capillaries and venules. These vessels are typically classified as those with diameters < 300 $$ <300 $$ μm and by several distinctive characteristics, such as mural cell coverage1 and resistance to flow.2 Structurally, arterioles and venules form branching structures which supply and drain an interconnected, mesh-like network of capillaries with diameters < 10 $$ <10 $$ μm.

Feb 7, 2024 | biorxiv.org | Paul Sweeney |Claire Walsh |Simon Walker-Samuel |Rebecca Shipley

AbstractWe present a 3D discrete-continuum model to simulate blood pressure in large microvascular tissues in the absence of known capillary network architecture. Our hybrid approach combines a 1D Poiseuille flow description for large, discrete arteriolar and venular networks coupled to a continuum-based Darcy model, point sources of flux, for transport in the capillary bed.

Nov 13, 2023 | meritalk.com | Claire Walsh

The use of AI and analytics are crucial for government agencies, who are among the largest owners of data. The benefits of AI are often discussed – operational efficiencies, intelligent automation possibilities and the ability to gain deeper insights from massive amounts of data. With the intense interest and proliferation of AI, governance of machine intelligence is getting more attention and appropriately so.

Mar 15, 2023 | mdpi.com | Claire Walsh |Lucie Gourmet |Simon Walker-Samuel |Natalie Aroha Holroyd

1. IntroductionEpiscopic microscopy refers to imaging techniques that utilize serial sectioning and block-face imaging to create high-resolution large-volume three-dimensional (3D) datasets. High Resolution Episcopic Microscopy (HREM) and its associated techniques (namely, Optical HREM, Episcopic fluorescent image capture (EFIC) and multi-fluorescent HREM (MF-HREM) (A)), require samples to be embedded in a supporting material to enable automated sectioning at the micron scale.