Simon Walker-Samuel

Aug 11, 2024 | octnews.org | Simon Walker-Samuel

August 11, 2024 | Ophthalmology | University College London, University of Cambridge, Moorfields Eye HospitalDisruption of retinal vasculature is linked to various diseases, including diabetic retinopathy and macular degeneration, leading to vision loss.

Jun 10, 2024 | nature.com | Keith Siew |Charlotte Nelson |Alessandra Grillo |Eliah G. Overbey |JangKeun Kim |Sanghee Yun | +41 more

AbstractMissions into Deep Space are planned this decade. Yet the health consequences of exposure to microgravity and galactic cosmic radiation (GCR) over years-long missions on indispensable visceral organs such as the kidney are largely unexplored.

Jun 10, 2024 | nature.com | Keith Siew |Charlotte Nelson |Alessandra Grillo |Eliah G. Overbey |JangKeun Kim |Sanghee Yun | +41 more

AbstractMissions into Deep Space are planned this decade. Yet the health consequences of exposure to microgravity and galactic cosmic radiation (GCR) over years-long missions on indispensable visceral organs such as the kidney are largely unexplored.

May 21, 2024 | onlinelibrary.wiley.com | Paul Sweeney |Claire Walsh |Simon Walker-Samuel |Rebecca Shipley

1 INTRODUCTION The microcirculation is a hierarchical structure of blood vessels consisting of arterioles, capillaries and venules. These vessels are typically classified as those with diameters < 300 $$ <300 $$ μm and by several distinctive characteristics, such as mural cell coverage1 and resistance to flow.2 Structurally, arterioles and venules form branching structures which supply and drain an interconnected, mesh-like network of capillaries with diameters < 10 $$ <10 $$ μm.

Mar 6, 2024 | biorxiv.org | Lucie Gourmet |Parag Mallick |Simon Walker-Samuel

AbstractThough the earliest stages of oncogenesis, post initiation, are not well understood, it is generally appreciated that a successful transition from a collection of dysregulated cells to an aggressive tumor requires complex ecological interactions between cancer cells and their environment. One key component of tumorigenesis is immune evasion. To investigate the interplay amongst the ecological behaviour of mutualism and immune evasion, we used a computational simulation framework.