Cuicui Wang

Jan 15, 2025 | pubs.acs.org | Wei Liu |Cuicui Wang |Yongfei Cui |Liangliang Chang

Nov 4, 2024 | nature.com | Xiaobing Zhai |Abao Xing |Gang Luo |Junfeng Li |Miao Zhou |Cuicui Wang | +7 more

Depression represents a significant global public health challenge, and marital status has been recognized as a potential risk factor. However, previous investigations of this association have primarily focused on Western samples with substantial heterogeneity. Our study aimed to examine the association between marital status and depressive symptoms across countries with diverse cultural backgrounds using a large-scale, two-stage, cross-country analysis. We used nationally representative, de-identified individual-level data from seven countries, including the USA, the UK, Mexico, Ireland, Korea, China and Indonesia (106,556 cross-sectional and 20,865 longitudinal participants), representing approximately 541 million adults. The follow-up duration ranged from 4 to 18 years. Our analysis revealed that unmarried individuals had a higher risk of depressive symptoms than their married counterparts across all countries (pooled odds ratio, 1.86; 95% confidence interval (CI), 1.61–2.14). However, the magnitude of this risk was influenced by country, sex and education level, with greater risk in Western versus Eastern countries (β = 0.36; 95% CI, 0.16–0.56; P < 0.001), among males versus females (β = 0.25; 95% CI, 0.003–0.47; P = 0.047) and among those with higher versus lower educational attainment (β2 = 0.34; 95% CI, 0.11–0.56; P = 0.003). Furthermore, alcohol drinking causally mediated increased later depressive symptom risk among widowed, divorced/separated and single Chinese, Korean and Mexican participants (all P < 0.001). Similarly, smoking was as identified as a causal mediator among single individuals in China and Mexico, and the results remained unchanged in the bootstrap resampling validation and the sensitivity analyses. Our cross-country analysis suggests that unmarried individuals may be at greater risk of depression, and any efforts to mitigate this risk should consider the roles of cultural context, sex, educational attainment and substance use. Analysing data from seven countries, this study found that unmarried individuals had a higher depression risk than married individuals. This risk was higher in Western countries, among males and among those with higher educational attainment.

May 1, 2024 | onlinelibrary.wiley.com | TAO WANG |Ying Chen |Cuicui Wang |Xuemin Ma

CONFLICT OF INTEREST STATEMENT The authors declare no conflicts of interest. Supporting Information Filename Description pce14933-sup-0001-NAC_Supplementary_tables_0206.docx27.5 KB Supporting information. pce14933-sup-0002-NAC3_supplementary0206.docx30.2 MB Supporting information. REFERENCES , , , , & (2018) An apple NAC transcription factor enhances salt stress tolerance by modulating the ethylene response. Physiologia Plantarum, 164, 279–289. , , , , , et al.

May 8, 2023 | physiciansweekly.com | Xu Zhang |Cuicui Wang |Chenwei Li |Hui Zhao

Lung cancer has significantly higher incidence and mortality rates worldwide. In this study, we analyzed the metabolic profiles of non-small cell lung cancer (NSCLC) patients and constructed prediction models for smokers and nonsmokers with internal validation. Plasma was collected from all patients enrolled for metabolic profiling by liquid chromatography-tandem mass spectrometry (LC-MS/MS). The total population was divided into two groups according to smoking or not.