Daming Zhou

May 8, 2024 | cell.com | Chang Liu |Daming Zhou |Aiste Dijokaite-Guraliuc

Highlights•BA.2.86, highly mutated from BA.2, is mapped in the landscape of recent variants•It is marginally less evasive than XBB.1.5 but escapes a panel of BA.2 antibodies•It has increased affinity for ACE2, possibly aiding transmission•Its RBD is primed for further escape at residues 455 and/or 456, as seen in JN.1SummaryBA.2.86, a recently described sublineage of SARS-CoV-2 Omicron, contains many mutations in the spike gene.

Apr 15, 2024 | nature.com | Chang Liu |Aiste Dijokaite-Guraliuc |Daming Zhou |Alexander J. Mentzer |Thomas Ritter |Nigel Temperton | +8 more

AbstractThe rapid evolution of SARS-CoV-2 is driven in part by a need to evade the antibody response in the face of high levels of immunity. Here, we isolate spike (S) binding monoclonal antibodies (mAbs) from vaccinees who suffered vaccine break-through infections with Omicron sub lineages BA.4 or BA.5. Twenty eight potent antibodies are isolated and characterised functionally, and in some cases structurally.

Mar 27, 2024 | nature.com | Daming Zhou |Aiste Dijokaite-Guraliuc |Alexander J. Mentzer |Nigel Temperton |Paul Klenerman |Susanna J. Dunachie | +3 more

AbstractUnder pressure from neutralising antibodies induced by vaccination or infection the SARS-CoV-2 spike gene has become a hotspot for evolutionary change, leading to the failure of all mAbs developed for clinical use. Most potent antibodies bind to the receptor binding domain which has become heavily mutated.

Jun 18, 2023 | articlegateway.com | Daming Zhou |Qin Hu |Yunnan Normal |Sun Yat-sen

Abstract Anthropology now plays a crucial role in the Global Social Governance. This article traces the development of cooperation between anthropology and international organizations from the perspective of anthropology's participation in the operation of international organizations' projects.