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Oct 8, 2024 | 
onlinelibrary.wiley.com | Daniel López-López |Ricardo Becerro-de-Bengoa-Vallejo |Marta Elena Losa-Iglesias |Madrid Spain
1 INTRODUCTION The increase in life expectancy is directly related to the increase in the population of elderly people.
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Sep 5, 2024 | 
peerj.com | Marta Elena Losa-Iglesias |Emmanuel Navarro-Flores |Daniel López-López |Hipólito Montesinos-Verdú
1Department of Nursing, Faculty of Nursing, Universidad Rey Juan Carlos, Madrid, Spain2Department of Nursing, Faculty of Nursing, Phisiotherapy and Podiatry, Universidad Complutense de Madrid, Madrid, Spain3Faculty of Nursing and Podiatry, Department of Nursing, University of Valencia, Frailty Research Organizaded Group.
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May 27, 2024 | 
nature.com | Ana M Pérez-Gutiérrez |Rosario Carmona |Carlos Loucera |Jorge A Cervilla |Blanca Gutierrez |Esther Molina | +3 more
AbstractMajor depression (MD) and obesity are complex genetic disorders that are frequently comorbid. However, the study of both diseases concurrently remains poorly addressed and therefore the underlying genetic mechanisms involved in this comorbidity remain largely unknown. Here we examine the contribution of common and rare variants to this comorbidity through a next-generation sequencing (NGS) approach.
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Mar 12, 2024 | 
dialnet.unirioja.es | Daniel López-López |Jose Galvan |Pedro V. Munuera-Martínez |Matilde García-Sánchez
Daniel López López [1] ; Rosa Mary de la Campa Portela [1] ; Marta Elena Losa Iglesias [2] ; José Ramos Galván [3] ; Pedro Vicente Munuera Martínez [3] ; Matilde García Sánchez [1] ; Ricardo Becerro de Bengoa Vallejo [4] [1] Universidade da Coruña Facultad de Enfermería y Podología Departamento de Ciencias de la Salud [2] Universidad Rey Juan Carlos Facultad Ciencias de la Salud [3] Universidad de Sevilla Facultad de Enfermería, Fisioterapia y Podología Departamento de Podología [4]...
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Oct 24, 2023 | 
nature.com | Javier Martinez-Trufero |Amancio Carnero |Daniel López-López
AbstractCyclin-dependent kinases 4 and 6 (CDK4/6) inhibitors demonstrated activity in terms of progression-free survival (PFS) in advanced dedifferentiated liposarcoma (DD-LPS), a sarcoma with CDK4 amplification. CDK4 overexpression is by far more common than amplification in sarcomas and it might be a rational target for CDK inhibitors.
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Jul 14, 2023 | 
frontiersin.org | Mary Sheehan |Carlo Biz |Daniel López-López
1. IntroductionAmputation causes disability, severely impairs human mobility and physical function, and has imposed a significant global health economic burden over the past several decades (1). The leading cause of amputation varies from region to region, peripheral vascular disease and diabetes have become the most important causes of amputation in developed countries (2, 3), which can be attributed to their escalating prevalence and the significant burden imposed on patients (4–6).
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Jul 8, 2023 | 
mdpi.com | Ricardo Becerro-de-Bengoa-Vallejo |Marta Elena Losa-Iglesias |Daniel López-López |Alfredo Medrano-Soriano
Open AccessArticle by Israel Casado-Hernández 1, Ricardo Becerro-de-Bengoa-Vallejo 1, Marta Elena Losa-Iglesias 2, Alfredo Medrano-Soriano 1, Daniel López-López 3, Emmanuel Navarro-Flores 4,*, Eduardo Pérez Boal 5 and Eva María Martínez-Jiménez 1 1 Faculty of Nursing, Physiotherapy and Podiatry, University Complutense of Madrid, 28040 Madrid, Spain 2 Faculty of Health Sciences, University Rey Juan Carlos, 28933 Móstoles, Spain 3 Research, Health, and Podiatry Group, Department of Health...
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Apr 19, 2023 | 
mdpi.com | Rocío Núñez-Torres |Guillermo Pita |María Peña-Chilet |Daniel López-López
Open AccessArticle by Rocio Nunez-Torres 1,*, Guillermo Pita 1, María Peña-Chilet 2,3,4, Daniel López-López 2,3,4, Jorge Zamora 1, Gema Roldán 2, Belén Herráez 1, Nuria Álvarez 1, María Rosario Alonso 1, Joaquín Dopazo 2,3,4,5 and Anna Gonzalez-Neira 1,6,* 1 Human Genotyping Unit (CEGEN), Cancer Genetics Program, National Cancer Research Center (CNIO), 28029 Madrid, Spain 2 Computational Medicine Platform, Fundación Progreso y Salud (FPS), Hospital Virgen del Rocío, 41013 Sevilla, Spain 3...
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Mar 8, 2023 | 
nature.com | Isabel Espadas |Michael Petr |Óscar Yanes |Maria Vinaixa |Daniel López-López |Jose Reyes | +9 more
AbstractATP-citrate lyase is a central integrator of cellular metabolism in the interface of protein, carbohydrate, and lipid metabolism. The physiological consequences as well as the molecular mechanisms orchestrating the response to long-term pharmacologically induced Acly inhibition are unknown.
