Dario Zocholl

Apr 19, 2024 | nature.com | Evelyne Gout |Kristoffer Weißert |Sandra Ammann |Ralf Kühn |Matthias Richter |Christine Molenda | +3 more

Correction to: Nature Immunology https://doi.org/10.1038/s41590-023-01420-5, published online 2 February 2023. In the version of the article initially published, Anja Schütz (Protein Production & Characterization Core Facility, Max-Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany), who produced the recombinant proteins used in this study, was inadvertently omitted from the author list. This has now been corrected in the PDF and HTML versions of the article.

Aug 8, 2023 | mentalhealth.bmj.com | Felix R. Fischer |Dario Zocholl |Geraldine Rauch |Brooke Levis

depression & mood disorders Arias de la Torre et al argue in ‘Population health surveys and screening tools for depressive disorders: aims and uses’ that population-based studies like the European Health Interview Survey (EHIS) are primarily intended to identify and compare vulnerable groups and factors associated with depression on a population level, not to estimate prevalence of major depressive disorders (MDD).1 We fully agree that the use of brief depression questionnaires in such...

Apr 6, 2023 | mentalhealth.bmj.com | Felix R. Fischer |Dario Zocholl |Geraldine Rauch |Brooke Levis

DiscussionWe incorporated the best available evidence on the diagnostic accuracy of the PHQ-8, using a cut-off of ≥10, to estimate major depression prevalence in Europe using data from the EHIS survey.

Feb 22, 2023 | nature.com | Evelyne Gout |Kristoffer Weißert |Sandra Ammann |Ralf Kühn |Matthias Richter |Christine Molenda | +3 more

Correction to: Nature Immunology https://doi.org/10.1038/s41590-023-01420-5. Published online 2 February 2023. In the version of this article originally published, there was an error in the order of magnitude for the units displayed on the y axes of the Figure 4g HBG (g/dl) panel and Figure 4h Triglycerides (mg/dl) panel, where the units now reading “20, 15, 10, 5, 0” and “200, 150, 100, 50, 0” appeared in error as “2,000, 1,500, 1,000, 500, 0” and “20,000, 15,000, 10,000, 5,000, 0,” respectively.

Feb 2, 2023 | nature.com | Evelyne Gout |Kristoffer Weißert |Sandra Ammann |Ralf Kühn |Matthias Richter |Hugues Lortat-Jacob | +3 more

AbstractInterferon-γ (IFNγ) is an important mediator of cellular immune responses, but high systemic levels of this cytokine are associated with immunopathology. IFNγ binds to its receptor (IFNγR) and to extracellular matrix (ECM) via four positively charged C-terminal amino acids (KRKR), the ECM-binding domain (EBD). Across evolution, IFNγ is not well conserved, but the EBD is highly conserved, suggesting a critical function.