Debojyoti Biswas

Nov 19, 2024 | biorxiv.org | Huanying Yeh |Yu Yang |Debojyoti Biswas |Noah Cowan

AbstractTo execute sensory-guided behavior, the nervous system must manage uncertainty within multiple streams of information. There are two highly nonlinear mechanisms for achieving this: 1) sensory reweighting, an internal neural computation which places more emphasis on sensory information that exhibits the least uncertainty, e.g. in a Bayesian framework, and 2) active sensing, an overt behavior that seeks to improve the quality of sensory information before it enters the nervous system.

Oct 17, 2024 | biorxiv.org | Yu Yang |Debojyoti Biswas |Noah Cowan |Huanying Yeh

AbstractAnimals integrate multiple sensory inputs to explore environments and execute locomotor behaviors. To carry out these behaviors, the nervous system internally reweights controller gains, putting more emphasis on those with the least uncertainty, e.g. in a Bayesian framework. Meanwhile, as sensory uncertainty increases, animals produce more vigorous active sensing movements.

Sep 19, 2024 | unite.ai | Debojyoti Biswas

Before we explore the sustainability aspect, let’s briefly recap how AI is already revolutionizing global logistics:Route Optimization, going far beyond simple GPS navigation. For instance, UPS's ORION (On-Road Integrated Optimization and Navigation) system uses advanced algorithms to optimize delivery routes. It considers factors like traffic patterns, package priorities, and promised delivery windows to create the most efficient routes. The result?

Nov 29, 2023 | nature.com | Tatsat Banerjee |Satomi Matsuoka |Debojyoti Biswas |Yuchuan Miao |Dhiman Sankar Pal |Masahiro Ueda | +1 more

AbstractThe plasma membrane is widely regarded as the hub of the numerous signal transduction activities. Yet, the fundamental biophysical mechanisms that spatiotemporally compartmentalize different classes of membrane proteins remain unclear. Using multimodal live-cell imaging, here we first show that several lipid-anchored membrane proteins are consistently depleted from the membrane regions where the Ras/PI3K/Akt/F-actin network is activated.

Oct 26, 2023 | nature.com | Debojyoti Biswas |Yu Yang |Eric Fortune |John Guckenheimer

AbstractTrade-offs between producing costly movements for gathering information (‘explore’) and using previously acquired information to achieve a goal (‘exploit’) arise in a wide variety of problems, including foraging, reinforcement learning and sensorimotor control. Determining the optimal balance between exploration and exploitation is computationally intractable, necessitating heuristic solutions.