Delphine Naquin

2 weeks ago | nature.com | Stéphane Pelletier |Virginie Marchand |Delphine Naquin |Jessica Andreani |Yuri Motorin |Benoît Palancade

AbstractSmall nucleolar RNAs are non-coding transcripts that guide chemical modifications of RNA substrates and modulate gene expression at the epigenetic and post-transcriptional levels. However, the extent of their regulatory potential and the underlying molecular mechanisms remain poorly understood. Here, we identify a conserved, previously unannotated intronic C/D-box snoRNA, termed snR107, hosted in the fission yeast long non-coding RNA mamRNA and carrying two independent cellular functions.