Robin Murray

Oct 25, 2024 | nature.com | Luis Alameda |Marta Di Forti |Celso Arango |Miguel Bernardo |Julio Bobes |Cristina Marta Del-Ben | +11 more

AbstractChildhood adversity is associated with various clinical dimensions in psychosis; however, how genetic vulnerability shapes the adversity-associated psychopathological signature is yet to be studied.

Oct 16, 2024 | bmj.com | David Nutt |Lucy Stafford |Robin Murray |Laura Stack

Intended for healthcare professionals News & ViewsShould recreational... Should recreational cannabis be legalised in the UK?

Oct 15, 2024 | nature.com | Emma Dempster |Eilis Hannon |Diego Quattrone |Edoardo Spinazzola |Zhikun Li |Charlotte Gayer-Anderson | +17 more

AbstractThe rising prevalence and legalisation of cannabis worldwide have underscored the need for a comprehensive understanding of its biological impact, particularly on mental health. Epigenetic mechanisms, specifically DNA methylation, have gained increasing recognition as vital factors in the interplay between risk factors and mental health.

Aug 1, 2024 | nature.com | Zhikun Li |Diptendu Mukherjee |Bea Duric |Diego Quattrone |Robin Murray |Edoardo Spinazzola

AbstractThe link between cannabis use and schizophrenia is well-established in epidemiological studies, especially among adolescents with early-onset use. However, this association in rodent models is less clear. This meta-analysis examined the effects of adolescent cannabinoid exposure on distinct schizophrenia-like behaviours in rodents and how experimental variations influence outcomes.

Jan 17, 2024 | nature.com | Sarah Tosato |Pentagiotissa Stefanatou |Robin Murray |Evangelos Vassos |Alex Hatzimanolis |Rigas-Filippos Soldatos

AbstractInsufficiency of vitamin D levels often occur in individuals with schizophrenia and first-episode psychosis (FEP). However, it is unknown whether this represents a biological predisposition, or it is essentially driven by illness-related alterations in lifestyle habits. Lower vitamin D has also been associated with adverse neurodevelopmental outcomes and predominant negative psychotic symptoms.