Elizabeth Crouch

Sep 30, 2024 | nature.com | Elizabeth Crouch |Kyle Jacobs |Lakyn Mayo |Jennifer Choi |Saba Shaikh |Arnold R. Kriegstein | +4 more

AbstractGerminal matrix hemorrhage (GMH) is a devastating neurodevelopmental condition affecting preterm infants, but why blood vessels in this brain region are vulnerable to rupture remains unknown. Here we show that microglia in prenatal mouse and human brain interact with nascent vasculature in an age-dependent manner and that ablation of these cells in mice reduces angiogenesis in the ganglionic eminences, which correspond to the human germinal matrix.

Sep 20, 2024 | nature.com | Elizabeth Crouch

A study using advanced single-cell technologies has broadened our understanding of the diversity and complexity of brain endothelial cells by uncovering new endothelial subtypes and transcriptional patterns. These findings offer insights into potential therapeutic targets and emphasize the need for further research on vascular lineages and neurovascular interactions.

Jul 18, 2023 | jamanetwork.com | Janice Probst |Elizabeth Crouch |Peiyin Hung |Steven H. Woolf

The New Crisis of Increasing All-Cause Mortality in US Children and Adolescents Steven H. Woolf, MD, MPH; Elizabeth R. Wolf, MD, MPH; Frederick P. Rivara, MD, MPH Increasing All-Cause Mortality in US Children and Adolescents—Reply Steven H. Woolf, MD, MPH; Elizabeth R. Wolf, MD, MPH; Frederick P. Rivara, MD, MPH To the Editor As public health researchers, we applaud the recent Viewpoint1 that called attention to recent increases in child mortality.