Engineering Programme

Sep 2, 2024 | ccforum.biomedcentral.com | Sheeja Prabhakaran |Sichuan province |Engineering Programme

The innate immune response plays a key role in the pathophysiology of sepsis. Upon activation, pattern recognition receptors (PRRs) initiate signaling cascades, leading to the nuclear translocation of NF-κB, interferon regulatory factor (IRF), and other transcription factors. These transcription factors initiate the production of pro-inflammatory cytokines, chemokines, type I interferons (IFNs), etc. [98].

Jun 21, 2024 | journals.plos.org | Xing Qian |Juan Zhou |Engineering Programme

Growth charts quantify age-related changes in body measurements and are used to monitor the growth and development in children from birth to school age. A recent seminal work modernized this concept for building normative charts of brain morphometric measures derived from structural magnetic resonance imaging (MRI), i.e., brain charts over the entire life-course [1].

Jun 4, 2024 | nutritionj.biomedcentral.com | Engineering Programme

Data for the present analysis are drawn from the Singapore Chinese Health Study (SCHS) – an ongoing population-based cohort study in Singapore that recruited 63,257 Chinese men and women aged 45–74 years between April 1993 and December 1998 [20]. Participants were citizens or permanent residents, of Chinese ethnicity and belonging to the two major dialect groups (Hokkien and Cantonese) and residing in public housing during the recruitment period.

Jun 3, 2024 | link.springer.com | Engineering Programme

AbstractIt is unclear if improving diet quality after midlife could reduce the risk of physical frailty at late life. We aimed to associate changes in diet quality after midlife with physical frailty at late life. Diet quality in 12,580 participants from the Singapore Chinese Health Study was assessed with the Dietary Approaches to Stop Hypertension (DASH) scores at baseline (1993–1998; mean age 53 years) and follow-up 3 (2014–2016; mean age 73 years).

Feb 28, 2024 | link.aps.org | Tingyu Qu |Engineering Programme |Michele Masseroni |Takashi Taniguchi

We investigate the magnetoresistance of a dual-gated bilayer MoS2 encapsulated by hexagonal boron nitride. At low magnetic fields (|B|<0.5T), we observe a negative magnetoresistance, which we identify as the weak localization effect. We determine both the phase coherence length and mean free path as a function of electron density and displacement field. Both characteristic lengths show a similar monotonic increase with electron density, while they are not affected by the displacement field.