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Aug 18, 2024 | 
bmjopen.bmj.com | Kim Tang |Elizabeth Hill |Elizabeth Pellicano |Craig Thompson
Barriers to and enablers of the transition from child and adolescent to adult mental health services for autistic young people and/or those with attention deficit hyperactivity disorder: protocol for a scoping review Statistics from Altmetric.com Request Permissions If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service.
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Aug 7, 2024 | 
elifesciences.org | Elizabeth Hill |Mark 'Stretch' Batchelor |Daljit Sangar |Kezia Jack
Accepted manuscript, PDF only. Full online edition to follow. Accepted ManuscriptAugust 7, 2024 Share this article Cite this article Syntaxin-6 delays prion protein fibril formation and prolongs presence of toxic aggregation intermediates eLife 13:e83320.
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Jul 21, 2024 | 
medrxiv.org | Fahri Küçükali |Elizabeth Hill |Tijs Watzeels |Holger Hummerich
AbstractBackground and ObjectivesPrions are misfolded prion protein assemblies that cause several fatal and transmissible neurodegenerative diseases, with the most common phenotype in humans being sporadic Creutzfeldt-Jakob disease (sCJD). However, aside from the prion protein itself, molecular risk factors are not well understood. Prion and prion-like mechanisms are thought to underpin common neurodegenerative disorders meaning that the elucidation of mechanisms could have broad relevance.
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Jul 16, 2024 | 
medrxiv.org | Hannah B Edwards |Carlos Sillero-Rejon |Hugh McLeod |Elizabeth Hill
The authors have declared no competing interest. This study was jointly funded by The Health Foundation (funder's reference 557668), the National Institute for Health and Care Research Applied Research Collaboration West (NIHR ARC West, core NIHR infrastructure funded: NIHR200181), and Health Innovation West of England (formerly the West of England Academic Health Science Network).
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Jun 27, 2024 | 
thorax.bmj.com | Renata L. Riha |Ankur Singh |Elizabeth Hill |Hazel J Evans
AbstractBackground In adults and children with intellectual disability (ID), sleep -disordered breathing (SDB) is thought to be common. However, large epidemiological studies are lacking, and there are few studies on optimal methods of investigation and even fewer randomised, controlled intervention trials of treatment. Method Peer-reviewed publications from various databases were examined in line with search terms relevant to ID and SDB spanning the years 200-2024.
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Jun 20, 2024 | 
phgfoundation.org | Rebecca Bazeley |Elizabeth Hill
The European Health Data Space Regulation has arrived but will its mandatory sharing requirement be its tour de force or Achilles’ heel? The Regulation amounts to an ambitious and laudable step towards a more integrated and streamlined approach to the secondary use of electronic health data. Such initiatives are, and will continue to be vital for the future of genomic research.
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Jun 5, 2024 | 
onlinelibrary.wiley.com | Adrienne Wilmot |Penelope A. Hasking |Suze Leitão |Elizabeth Hill
Whole school initiatives to promote school-connectedness are needed to support the mental health of children with dyslexia Researchers and clinicians can work with school communities to better understand how to promote school-connectedness among children with dyslexia 1 INTRODUCTION Reading difficulties characterised by poor phonetic decoding, spelling and reading fluency affect up to 10% of children (Brimo et al., 2021; Castles et al., 2010), a figure that equates to approximately 2–4...
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Feb 5, 2024 | 00016-6/abstract&sz=64)
thelancet.com | sarah griffiths |Mark E. Boyes |Elizabeth Hill
Developmental language disorder (DLD) is the consensus term for neurodivergence characterised by challenges with speaking and listening that restrict communication. Difficulties with speaking might manifest as delayed early language milestones, saying less overall, and use of simple sentences with reduced vocabulary, which are difficult for listeners trying to follow the child's intended meaning.
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Jan 11, 2024 | 
scienceopen.com | Elizabeth Hill |Thomas Cunningham
Two substrates of insulin-degrading enzyme (IDE), amyloid beta-protein (Abeta) and insulin, are critically important in the pathogenesis of Alzheimer's disease (AD) and type 2 diabetes mellitus (DM2), respectively. We previously identified IDE as a principal regulator of Abeta levels in neuronal and microglial cells. A small chromosomal region containing a mutant IDE allele has been associated with hyperinsulinemia and glucose intolerance in a rat model of DM2.
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Nov 9, 2023 | 
onlinelibrary.wiley.com | Chun-Che Wen |Nathaniel Baker |Rajib Paul |Elizabeth Hill
CONFLICT OF INTEREST STATEMENT Kevin M. Gray has received research support from Aelis Farma and has provided consultation to Pfizer, Inc., and Jazz Pharmaceuticals. Supporting Information Filename Description sim9945-sup-0001-Supinfo.zipZip archive, 3.2 MB OnlineSupplement REFERENCES 1, , , . The reliability of the Alcohol Timeline Followback when administered by telephone and by computer. Drug Alcohol Depend. 1996; 42(1): 49-54. doi:10.1016/0376-8716(96)01263-X 2.
