Frederico C Kiffer

Sep 25, 2024 | onlinelibrary.wiley.com | Sanghee Yun |Frederico C Kiffer |Grace L. Bancroft |Caterina S. Guzman

33-beam-GCR 33-beam galactic cosmic radiation 3-CSI 3-chamber social interaction AALAC Association for Assessment and Accreditation of Laboratory Animal Care Acq acquisition BLAF Brookhaven Laboratory Animal Facility BNL Brookhaven National Laboratory CDDO-EA 2-cyano-3, 12-dioxooleana-1, 9-dien-28-oic acid-ethylamide CNS central nervous system DCX doublecortin DCX+ doublecortin-immunoreactive EPM elevated plus maze Ext extinction GCR galactic cosmic radiation h hour(s) Hab habituation IACUC...

Jun 10, 2024 | nature.com | Keith Siew |Charlotte Nelson |Alessandra Grillo |Eliah G. Overbey |JangKeun Kim |Sanghee Yun | +41 more

AbstractMissions into Deep Space are planned this decade. Yet the health consequences of exposure to microgravity and galactic cosmic radiation (GCR) over years-long missions on indispensable visceral organs such as the kidney are largely unexplored.

Jun 10, 2024 | nature.com | Keith Siew |Charlotte Nelson |Alessandra Grillo |Eliah G. Overbey |JangKeun Kim |Sanghee Yun | +41 more

AbstractMissions into Deep Space are planned this decade. Yet the health consequences of exposure to microgravity and galactic cosmic radiation (GCR) over years-long missions on indispensable visceral organs such as the kidney are largely unexplored.

Apr 15, 2024 | biorxiv.org | Sanghee Yun |Ivan Soler |Frederico C Kiffer |Catalina S Guzman

AbstractGalactic cosmic radiation (GCR) is an unavoidable risk to astronauts that may affect mission success. Male rodents exposed to 33-beam-GCR (33-GCR) show short-term cognitive deficits but reports on female rodents and long-term assessment is lacking. Here we asked: What are the longitudinal behavioral effects of 33-GCR on female mice? Also, can an antioxidant/anti-inflammatory compound mitigate the impact of 33-GCR?