Giorgio Stassi

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Membrane to cortex attachment determines different mechanical phenotypes in LGR5+ and LGR5- colorectal cancer cells - Nature Communications

Apr 17, 2024 | nature.com | Valeria Venturini |Adrià Cañellas-Socias |Camille Stephan-Otto Attolini |Catherine Xu |Giorgio Stassi |Pere Roca-Cusachs | +4 more

AbstractColorectal cancer (CRC) tumors are composed of heterogeneous and plastic cell populations, including a pool of cancer stem cells that express LGR5. Whether these distinct cell populations display different mechanical properties, and how these properties might contribute to metastasis is poorly understood.

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