Camille Stephan-Otto Attolini

Featured in: Favicon

Articles

Membrane to cortex attachment determines different mechanical phenotypes in LGR5+ and LGR5- colorectal cancer cells - Nature Communications

Apr 17, 2024 | nature.com | Valeria Venturini |Adrià Cañellas-Socias |Camille Stephan-Otto Attolini |Catherine Xu |Giorgio Stassi |Pere Roca-Cusachs | +4 more

AbstractColorectal cancer (CRC) tumors are composed of heterogeneous and plastic cell populations, including a pool of cancer stem cells that express LGR5. Whether these distinct cell populations display different mechanical properties, and how these properties might contribute to metastasis is poorly understood.
Structure and mechanisms of transport of human Asc1/CD98hc amino acid transporter - Nature Communications

Apr 6, 2024 | nature.com | Maria Martinez-Molledo |Paola Bartoccioni |Ignasi Puch-Giner |Camille Stephan-Otto Attolini |Rafael Artuch |Lucia Diaz | +6 more

AbstractRecent cryoEM studies elucidated details of the structural basis for the substrate selectivity and translocation of heteromeric amino acid transporters. However, Asc1/CD98hc is the only neutral heteromeric amino acid transporter that can function through facilitated diffusion, and the only one that efficiently transports glycine and D-serine, and thus has a regulatory role in the central nervous system.

Try JournoFinder For Free

Search and contact over 1M+ journalist profiles, browse 100M+ articles, and unlock powerful PR tools.