Haitao Ding

Oct 29, 2024 | nature.com | Hongxing Shen |Oluwagbemiga Ojo |Haitao Ding |Zach Lewis |Ewa Podgorska |James A. Bonner

AbstractHypoxia is a common feature in various pathophysiological contexts, including tumor microenvironment, and IFN-γ is instrumental for anti-tumor immunity. HIF1α has long been known as a primary regulator of cellular adaptive responses to hypoxia, but its role in IFN-γ induction in hypoxic T cells is unknown. Here, we show that the HIF1α-glycolysis axis controls IFN-γ induction in both human and mouse T cells, activated under hypoxia.

Apr 30, 2023 | mdpi.com | Ke He |Haitao Ding |Nan Xu |Konghui Guo

This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessArticleby, *, and State Key Laboratory of Automotive Simulation and Control, Jilin University, Changchun 130025, China*Author to whom correspondence should be addressed. Appl. Sci.

Apr 6, 2023 | mdpi.com | Ke He |Haitao Ding |Nan Xu |Konghui Guo

4. Results and DiscussionA road network was first constructed to verify the lane-level routing algorithm using RoadRunner [33]. This interactive editor allows us to design 3D scenes for simulating and testing automated driving systems. Then, the OpenDrive file exported from RoadRunner was imported into SCANeR studio [34] to build an ultra-realistic virtual driving scene.