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Oct 4, 2024 | 
nature.com | Hang Xu |Qiang Wei
AbstractTreatment with androgen-ablative therapies effectively inhibited androgen receptor (AR)-positive (AR+) prostate cancer (PCa) cell subtypes, but it resulted in an increase in AR-negative (AR−) PCa cell subtypes. The present study aimed to investigate the debated mechanisms responsible for the changing proportion of cell types, identifying CXCL8 as a synthetic essential effector of AR− PCa cells.
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Oct 2, 2024 | 
mdpi.com | Qingyue Wang |Zihao Yuan |Hang Xu |Yuan Chen
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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Aug 20, 2024 | 
mdpi.com | Hang Xu
This is an early access version, the complete PDF, HTML, and XML versions will be available soon.
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Jun 21, 2024 | 
nature.com | Yahui Long |Kok Siong Ang |Raman Sethi |Lynn van Olst |Hang Xu |Lai Guan Ng | +3 more
AbstractAdvances in spatial omics technologies now allow multiple types of data to be acquired from the same tissue slice. To realize the full potential of such data, we need spatially informed methods for data integration. Here, we introduce SpatialGlue, a graph neural network model with a dual-attention mechanism that deciphers spatial domains by intra-omics integration of spatial location and omics measurement followed by cross-omics integration.
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May 7, 2024 | 
mdpi.com | Hang Xu
This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessArticlebyHang Xu SciProfilesScilitPreprints.orgGoogle ScholarHang Xu received a B.S. degree in software engineering from Xiamen University, China, in 2012, and a [...]Hang Xu received a B.S. degree in software engineering from Xiamen University, China, in 2012, and a Ph.D. degree in computer science and technology from Xiamen University, China, in 2018.
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Apr 14, 2024 | 
mdpi.com | Hang Xu |Chaohui Huang |Min Lin |Jianbing Lin
All articles published by MDPI are made immediately available worldwide under an open access license. No specialpermission is required to reuse all or part of the article published by MDPI, including figures and tables. Forarticles published under an open access Creative Common CC BY license, any part of the article may be reused withoutpermission provided that the original article is clearly cited. For more information, please refer tohttps://www.mdpi.com/openaccess.
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Feb 18, 2024 | 
arxiv.org | Hang Xu
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Dec 2, 2023 | 
onlinelibrary.wiley.com | Hang Xu |Lin Zhou |Li-Li Xu |Bao-Yan Wang
CONFLICT OF INTEREST STATEMENT The authors declared that they have no conflicts of interest regarding this work. Supporting Information Filename Description tox24063-sup-0001-FigureS1.tifTIFF image, 5.8 MB Figure S1. HE staining of different organs of sham-operated mice and MI mice with or without PAGln treatment. tox24063-sup-0002-FigureS2.tifTIFF image, 2.3 MB Figure S2. PAGln PAGln pretreatment enhanced H2O2-induced inhibition on H9C2 activity.
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Nov 28, 2023 | 
mdpi.com | Qiaoyun Wu |Hang Xu |Zhifeng Xu |Xuyong Chen
All articles published by MDPI are made immediately available worldwide under an open access license. No specialpermission is required to reuse all or part of the article published by MDPI, including figures and tables. Forarticles published under an open access Creative Common CC BY license, any part of the article may be reused withoutpermission provided that the original article is clearly cited. For more information, please refer tohttps://www.mdpi.com/openaccess.
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Oct 24, 2023 | 
mdpi.com | Hang Xu |Yi Zuo |Jian Wei |Lei Wang
1. IntroductionFrom lower organisms to higher living organisms, circadian clocks have evolved continuously to adapt to environmental changes. During its evolution, the circadian clock system has recruited more components to form an intricate, self-sustaining network.
