Haruka Hamanoue

Oct 13, 2024 | nature.com | Shinichi Namba |Masato Akiyama |Haruka Hamanoue |Itaru Kushima |Koichi Matsuda |Masahiro Nakatochi | +4 more

Private enterprises offer preimplantation genetic testing with polygenic scores to select embryos with ‘desirable’ potential. In silico simulations using biobank resources show that the selected embryo would rely substantially on the choice of polygenic score method and randomness in score construction, which raises ethical concerns.