Hassan Awada

May 11, 2024 | nature.com | Hussein Awada |Tariq Kewan |Danai Dima |Hassan Awada |Simona Pagliuca |Valeria Visconte

To the Editor:Karyotypic aberrations of chromosome (chr) 6 include duplications (trisomy 6 [+6]), deletions of its short arm (del6p), uniparental disomy 6p (UPD6p), as well as various microduplications and microdeletions. Lesions involving 6p are of particular interest as they point toward HLA locus involvement, including loss of heterozygosity and/or haploinsufficiency, as pathogenic drivers resulting from deletions and UPD6p [1, 2].

Apr 29, 2024 | nature.com | Hussein Awada |Valeria Visconte |Hassan Awada |James Cook

AbstractTherapy-related myeloid neoplasms (tMN) are complications of cytotoxic therapies. Risk of tMN is high in recipients of autologous hematopoietic stem cell transplantation (aHSCT). Acquisition of genomic mutations represents a key pathogenic driver but the origins, timing and dynamics, particularly in the context of preexisting or emergent clonal hematopoiesis (CH), have not been sufficiently clarified.

Nov 3, 2023 | newsbreak.com | Hassan Awada

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