Helen Hope

Apr 24, 2024 | nature.com | Matteo Morotti |Alizée J. Grimm |Helen Hope |Marion Arnaud |David Barras |Catherine Ronet | +14 more

AbstractExpansion of antigen-experienced CD8+ T cells is critical for the success of tumour-infiltrating lymphocyte (TIL)-adoptive cell therapy (ACT) in patients with cancer1. Interleukin-2 (IL-2) acts as a key regulator of CD8+ cytotoxic T lymphocyte functions by promoting expansion and cytotoxic capability2,3.

Nov 16, 2023 | wellandgood.com | Helen Hope

Fitness Fitness Tips Pin It Photo: Getty Images/Igor Alecsander Towards the end of every year, I catch myself lamenting how much my health and fitness routines have slipped in the run-up to the holiday season. Oh well, I’ll just harness that New Year’s resolution energy in January, I think to myself.

Nov 15, 2023 | wellandgood.com | Helen Hope

You’ve been breathing your whole life, so it should be easy to just “take a deep breath”... right? If you’ve ever seriously struggled to match the pace of structured breathwork in a yoga class or guided meditation, you know it’s not always that simple. Alex Artymiak, yoga, meditation, and breath-work teacher based in Santa Monica, California Jasmine Marie, breathworker and founder of Black Girls Breathing Michael J.

Sep 1, 2023 | breathe.ersjournals.com | Rachel Daly |Lynn Elsey |Helen Hope |Siobhan Ludlow

IntroductionRespiratory symptoms such as dyspnoea, chest and throat tightness, cough, and noisy breathing are nonspecific, and clinical assessment and testing are required to make a diagnosis. Many patients have persistent symptoms either in the absence of an obvious cause or when the most obvious cause has been adequately treated. We use the term “complex breathlessness” to describe this presentation, as also defined in the ERS Monograph in 2022 [1].

Aug 31, 2023 | nature.com | Yi-Hsuan Chiang |Pierpaolo Ginefra |Helen Hope |Charles Bataclan |Yi-Ru Yu |Frédérica Schyrr | +1 more

AbstractAging compromises hematopoietic and immune system functions, making older adults especially susceptible to hematopoietic failure, infections and tumor development, and thus representing an important medical target for a broad range of diseases. During aging, hematopoietic stem cells (HSCs) lose their blood reconstitution capability and commit preferentially toward the myeloid lineage (myeloid bias)1,2. These processes are accompanied by an aberrant accumulation of mitochondria in HSCs3.