Hemant Joshi

Far Western, Kathmandu

Sub-Editor at National News Agency (RSS)

Sub-Editor at National News Agency (RSS) |Former Sub-Editor: @ekantipur_com | Mass-Com. & Journalism educator.

Articles

Unsymmetrical NNE (E = S, Se) Pincer Palladium(II) Complexes: Syntheses, Structure, and Catalytic Activity in Decarboxylative Heteroarylation of Coumarin-3-carboxylic Acids

2 months ago | pubs.acs.org | Prakash N. Swami |Neha Meena |Hemant Joshi |Ram Kinkar Roy
Pd(II) NCSe-Pincer Complexes for Regioselective Cross-Dehydrogenative Coupling of Arylthiophenes with Hetero(arenes)

Dec 6, 2024 | pubs.rsc.org | Hemant Joshi |Sohan Singh |Suman Mahala |Nattamai Bhuvanesh

Pd(II) NCSe-Pincer Complexes for Regioselective Cross-Dehydrogenative Coupling of Arylthiophenes with Hetero(arenes) Herein, we have presented the synthesis of two new NCSe pincer ligands by the reaction of 3-((phenylselanyl)methoxy)benzaldehyde (P) with alkyl amines (tbutylamine (L1) and 1-adamantylamine (L2)). The reaction of ligands L1 and L2 with PdCl2(CH3CN)2 precursor resulted in the formation of palladium pincer complexes C1 and C2, respectively.
Investment summit ends with signing of important agreements

Apr 28, 2024 | risingnepaldaily.com | Hemant Joshi

By Hemant Joshi, Kathmandu, April 29: The two-day third Nepal Investment Summit 2024 concluded here on Monday with the signing of some significant agreements while also laying the founding for bringing in more investments into the country. The notable participation of domestic and foreign investors, along with some significant outcome has conveyed the message that Nepal is an attractive destination for investment, said Chief Executive Officer of Investment Board Nepal (IBN), Sushil Bhatta.
Palladium(II) NCS‐Pincer Complexes Mediated Regioselective Cross Dehydrogenative Alkenation of 2‐Arylthiophenes

Mar 18, 2024 | chemistry-europe.onlinelibrary.wiley.com | Sohan Singh |Suman Mahala |Nattamai Bhuvanesh |Hemant Joshi

Supporting Information As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors.
A detailed molecular network map and model of the NLRP3 inflammasome

Nov 15, 2023 | frontiersin.org | Chaofeng Han |Shuobing Chen |Hemant Joshi |Jack Green

IntroductionThe innate immune system serves as an immediate and essential defence towards exogenous and endogenous threats. Its activity is influenced by a number of pattern-recognition receptors (PRRs) that recognize pathogen- and damage-associated molecular patterns (PAMPs/DAMPs).
The Pharmacological Implications of Flavopiridol: An Updated Overview

Nov 10, 2023 | mdpi.com | Hemant Joshi |Hardeep Singh Tuli |Anuj Ranjan |Abhishek Chauhan

All articles published by MDPI are made immediately available worldwide under an open access license. No specialpermission is required to reuse all or part of the article published by MDPI, including figures and tables. Forarticles published under an open access Creative Common CC BY license, any part of the article may be reused withoutpermission provided that the original article is clearly cited. For more information, please refer tohttps://www.mdpi.com/openaccess.
Data Management - SAP BW on HANA

Sep 18, 2023 | blogs.sap.com | Hemant Joshi

When your SAP BW system runs on HANA database, the cost of putting all the data in HANA in-memory is high. Also not all data from SAP BW is required in HANA database and only 30-40% of data from BW is actively required for reporting and operations. This data should only be put to HANA in-memory capabilities. SAP BW on HANA provides a setting for active and non-active data so that you can manage the lower total cost of ownership.
Generation of antigen-specific memory CD4 T cells by heterologous immunization enhances the magnitude of the germinal center response upon influenza infection

Aug 31, 2023 | biorxiv.org | Hemant Joshi |Andrew Baessler |Ignacio Mena |Adolfo Garcia-Sastre

AbstractCurrent influenza vaccine strategies have yet to overcome significant obstacles, including rapid antigenic drift of seasonal influenza viruses, in generating efficacious long-term humoral immunity. Due to the necessity of germinal center formation in generating long-lived high affinity antibodies, the germinal center has increasingly become a target for the development of novel or improvement of less-efficacious vaccines.
Substrate stiffness can affect the crosstalk between adipose derived mesenchymal stem cells and macrophages in bone tissue engineering

Jul 27, 2023 | frontiersin.org | Estrela Neto |Dalong Ni |Hemant Joshi |Andrey Elchaninov

Zeyang Liu1,2 Jin Liu1,2 Jipeng Li1,2 Yinwei Li1,2 Jing Sun1,2 Yuan Deng1,2* Huifang Zhou1,2* 1Department of Ophthalmology, Shanghai Ninth People’s Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China 2Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Shanghai Ninth People’s Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China Purpose: This study aimed to explore the effect of biomaterials with different stiffness on Adipose...
Tumor-derived GDF-15 blocks LFA-1 dependent T cell recruitment and suppresses responses to anti-PD-1 treatment - Nature Communications

Jul 20, 2023 | nature.com | Carmen Reitinger |Kilian Wistuba-Hamprecht |Hubert Hackl |Hemant Joshi |Phil Cheng |Mitchell Levesque | +13 more

Proteins and antibodiesHIS-tagged recombinant human Growth and Differentiation Factor-15 was produced in HEK293T cells (Invigate GmbH, Jena). The anti-human GDF-15 antibody used in this manuscript was generated in female C57BL/6J GDF-15-/–mice kindly provided by Dr. Jens Strelau (Heidelberg, Germany) and validated for binding affinity by surface plasmon resonance at NMI (Reutlingen, Germany). Specificity was tested by tissue cross-reactivity studies.

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Hemant R. Joshi @HemantRajjoshi

25 May 25

...काठमाडौँमा मात्र किन? ब्वाँसो, हुँडार, मलसाँप्रोका झुण्डहरु देशभर कब्जा हान। अमुक तन्त्रको उत्सव मनाउ।

Hemant R. Joshi @HemantRajjoshi

23 May 25

वाम नजरियाले हाम्रो अर्थतन्त्र बुझ्न यी पुस्तक उपयोगी छन। तर उदारवाद र पुँजीवादलाई निस्तेज गरेर मात्रै सुधार सम्भव छ भन्ने दावीसँग असहमत।अर्थशास्त्रीले कुनै `वाद´को मात्र पक्षपोषण गर्दा तथ्यपरकता मर्छ। अरु विषयवस्तुका हिसाबले दुवै पढ्न लायक छन। @Harirokaa @nibartaman https://t.co/7m7cjkFV8x

Hemant R. Joshi @HemantRajjoshi

22 May 25

RT @MrRshahi: Made in बिदेश, packaging & Export from नेपाल ! https://t.co/WowrAdgGbC

Hemant Joshi

Articles

Unsymmetrical NNE (E = S, Se) Pincer Palladium(II) Complexes: Syntheses, Structure, and Catalytic Activity in Decarboxylative Heteroarylation of Coumarin-3-carboxylic Acids

Pd(II) NCSe-Pincer Complexes for Regioselective Cross-Dehydrogenative Coupling of Arylthiophenes with Hetero(arenes)

Investment summit ends with signing of important agreements

Palladium(II) NCS‐Pincer Complexes Mediated Regioselective Cross Dehydrogenative Alkenation of 2‐Arylthiophenes

A detailed molecular network map and model of the NLRP3 inflammasome

The Pharmacological Implications of Flavopiridol: An Updated Overview

Data Management - SAP BW on HANA

Generation of antigen-specific memory CD4 T cells by heterologous immunization enhances the magnitude of the germinal center response upon influenza infection

Substrate stiffness can affect the crosstalk between adipose derived mesenchymal stem cells and macrophages in bone tissue engineering

Tumor-derived GDF-15 blocks LFA-1 dependent T cell recruitment and suppresses responses to anti-PD-1 treatment - Nature Communications

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