Jack Green

Aug 7, 2024 | nature.com | Jiayu Cao |Stefan Roth |Anna Kopczak |Yaw Asare |Marios K. Georgakis |Jack Green | +12 more

AbstractThe risk of early recurrent events after stroke remains high despite currently established secondary prevention strategies1. Risk is particularly high in patients with atherosclerosis, with more than 10% of patients experiencing early recurrent events1,2. However, despite the enormous medical burden of this clinical phenomenon, the underlying mechanisms leading to increased vascular risk and recurrent stroke are largely unknown.

Nov 15, 2023 | frontiersin.org | Chaofeng Han |Shuobing Chen |Hemant Joshi |Jack Green

IntroductionThe innate immune system serves as an immediate and essential defence towards exogenous and endogenous threats. Its activity is influenced by a number of pattern-recognition receptors (PRRs) that recognize pathogen- and damage-associated molecular patterns (PAMPs/DAMPs).