Hong Xie

Sep 8, 2024 | onlinelibrary.wiley.com | Hong Xie |Yinxue Guo |Hang Jin |Pingyu Ge

1 INTRODUCTION Hyperuricemia (HUA) represents a metabolic disorder by dysregulation in purine metabolism, resulting in either excessive production or reduced excretion of uric acid, thereby leading to elevated blood uric acid levels.1 It is clinically defined as serum uric acid levels equal to or greater than 420 μmol/L in males and 360 μmol/L in females.2 Within normal ranges, blood uric acid levels exhibit anti-inflammatory, antioxidant and vasodilatory properties.

Aug 26, 2024 | arxiv.org | Liming Wang |Hong Xie |Mingqiang Zhou

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Jul 12, 2024 | nature.com | Hong Xie

AbstractMemory engrams are a subset of learning activated neurons critical for memory recall, consolidation, extinction and separation. While the transcriptional profile of engrams after learning suggests profound neural changes underlying plasticity and memory formation, little is known about how memory engrams are selected and allocated. As epigenetic factors suppress memory formation, we developed a CRISPR screening in the hippocampus to search for factors controlling engram formation.

Jul 4, 2024 | onlinelibrary.wiley.com | Jeong-Bon Kim |Le Luo |Hong Xie

Using a large sample of US firms over the period of 1991–2015, we examine the economic benefits of paying dividends. We find that dividend payments mitigate stock price crash risk. We show that dividend payments reduce bad news hoarding (overinvestments) while bad news hoarding (overinvestments) is (are) positively associated with stock price crash risk, suggesting that curbing bad news hoarding and curtailing overinvestments are two channels through which dividends mitigate crash risk.

Jun 11, 2024 | mdpi.com | Ruihuan Su |Daoyang Yuan |Hong Xie |Aiguo Wang

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