-
Dec 10, 2024 | 
pubs.rsc.org | Zhenhua Guan |Hubei Province |Nanyu Yao |Wenling Yuan
Total biosynthesis of cotylenin diterpene glycosides as 14-3-3 protein–protein interaction stabilizers†
Cotylenins (CNs) are bioactive fungal diterpene glycosides that exhibit stabilizing activity on 14-3-3 protein–protein interactions (PPIs), which has significant therapeutic potential. Although CNs were isolated as early as 1970, their biosynthetic pathway has remained unclear, and their limited supply has hindered further research.
-
Dec 6, 2024 | 
pubs.rsc.org | Shengnan Zhang |Hubei Province |South-Central Minzu
Facet-dependent hematite reactivity in Cr(vi) removal with Fe(ii)†
Hematite displays diverse crystal structures and often coexists with Fe(II), both of which are crucial in controlling the fate and mobility of Cr(VI). However, the mechanisms underlying Cr(VI) removal in the presence of Fe(II) on various hematite facets remain elusive.
-
Nov 14, 2024 | 
molecular-cancer.biomedcentral.com | Hubei Province
The insights into the TIME of LM provide a theoretical basis for intervention in the course of LM development through immunological mechanisms (Fig. 6). Modifying the existing immune crosstalk within the TIME holds promise for disrupting the existing prometastatic balance (Table 1). Introducing new immune components from outside can help the host respond to the development of LM, either actively or passively, achieving a counterbalance.
-
Oct 18, 2024 | 
journals.plos.org | Xiaobing Gao |Hubei Province |Xi Zhang |Suhua Shao
Loading metrics Open Access Peer-reviewedResearch Article Citation: Gao X, Shao S, Zhang X, Li C, Jiang Q, Li B (2024) Interaction between CD244 and SHP2 regulates inflammation in chronic obstructive pulmonary disease via targeting the MAPK/NF-κB signaling pathway. PLoS ONE 19(10): e0312228.
-
Oct 16, 2024 | 00205-0?rss=yes&sz=64)
cell.com | Hubei Province
Keywordswound healingneutrophilsneutrophil extracellular trapsNET-targeted therapyimmune regulationGet full text accessLog in, subscribe or purchase for full access. References1. Herre, M. ... Neutrophil extracellular traps in the pathology of cancer and other inflammatory diseasesPhysiol. Rev. 2023; 103:277-3122. Poli, V. ∙ Zanoni, I. Neutrophil intrinsic and extrinsic regulation of NETosis in health and diseaseTrends Microbiol. 2023; 31:280-2933. Zhu, S. ...
-
Sep 18, 2024 | 
jmedicalcasereports.biomedcentral.com | Hubei Province
ReferencesHudson A, Sturgeon A, Peiris A. Tinea Versicolor. JAMA. 2018;320(13):1396. Article PubMed Google Scholar Cullingham K, Hull PR. Atrophying pityriasis versicolor. CMAJ. 2014;186(10):447–50. https://doi.org/10.1503/cmaj.131846. Article Google Scholar Huang WW, et al. A Case of tinea versicolor of the eyelids. Pediatric Dermatol. 2012. https://doi.org/10.1111/j.1525-1470.2012.01753.x.Article Google Scholar Hudson A, Carroll B, Kim SJ. Folliculocentric tinea versicolor. Dermatol Online J. 2017.
-
Aug 8, 2024 | 
academic.oup.com | Hubei Province |Sun Yat-sen
Impaired extravillous trophoblast (EVT) invasion and resulted poor placentation play a vital role in the development of preeclampsia (PE). However, the underlying mechanisms of dysregulated EVTs remain unclear. This study aimed to explore the role of poly (C)-binding protein 2 (PCBP2), a multifunctional RNA binding protein, in the pathogenesis of PE and to investigate the detailed signaling pathway.
-
Jun 14, 2024 | 
pubs.aip.org | Zhejiang Province |Hubei Province |Zengshun Chen |Hamidreza Eivazi
Precise estimation of the thermal updraft environment is important for the effective exploration of wind resources in long-endurance drones. Nevertheless, previous regression algorithms exhibit limitations in accurately evaluating updrafts under new operating conditions, and traditional airborne wind measurement methods are constrained by narrow ranges and sparse spatial sampling. This study addresses these challenges by harnessing continuous temperature data acquired via infrared sensors.
-
Apr 17, 2024 | 00407-4/abstract?rss=yes&sz=64)
ejso.com | Hubei Province
These cookies are necessary for the website to function and cannot be switched off in our systems. They are usually only set in response to actions made by you which amount to a request for services, such as setting your privacy preferences, logging in or filling in forms. You can set your browser to block or alert you about these cookies, but some parts of the site will not then work. These cookies do not store any personally identifiable information.
-
Jan 31, 2024 | 00721-3/abstract&sz=64)
academicradiology.org | Hubei Province
These cookies are necessary for the website to function and cannot be switched off in our systems. They are usually only set in response to actions made by you which amount to a request for services, such as setting your privacy preferences, logging in or filling in forms. You can set your browser to block or alert you about these cookies, but some parts of the site will not then work. These cookies do not store any personally identifiable information.
