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Dec 28, 2024 | 
mdpi.com | Hui Yang
This is an early access version, the complete PDF, HTML, and XML versions will be available soon.
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Dec 12, 2024 | 
nature.com | Hui Yang
AbstractDuplication of methyl-CpG-binding protein 2 (MECP2) gene causes MECP2 duplication syndrome (MDS). To normalize the duplicated MECP2 in MDS, we developed a high-fidelity Cas13Y (hfCas13Y) system capable of targeting the MECP2 (hfCas13Y-gMECP2) messenger RNA for degradation and reducing protein levels in the brain of humanized MECP2 transgenic mice.
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Nov 19, 2024 | 
nature.com | Wei Zhu |Wei Hua |Hui Yang
AbstractGliomas exhibit high heterogeneity and poor prognosis. Despite substantial progress has been made at the genomic and transcriptomic levels, comprehensive proteomic characterization and its implications remain largely unexplored. In this study, we perform proteomic profiling of gliomas using 343 formalin-fixed and paraffin-embedded tumor samples and 53 normal-appearing brain samples from 188 patients, integrating these data with genomic panel information and clinical outcomes.
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Nov 18, 2024 | 
onlinelibrary.wiley.com | Hongyu Chu |Yanni Li |Hui Yang |Yuhang LIU
European Association for the Study of the Liver. Electronic Address: [email protected], European Association for the Study of the LiverEASL Clinical Practice Guidelines: The Diagnosis and Management of Patients With Primary Biliary Cholangitis
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Sep 30, 2024 | 
mdpi.com | Hui Yang |Qing Sun |Jiaxin Yuan
This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessArticle by Hui Yang SciProfiles Scilit Preprints.org Google Scholar , Qing Sun SciProfiles Scilit Preprints.org Google Scholar and Jiaxin Yuan SciProfiles Scilit Preprints.org Google Scholar * College of Air Transportation, Shanghai University of Engineering Science, Shanghai 201620, China *Author to whom correspondence should be addressed.
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Aug 27, 2024 | 
mdpi.com | Bin Chen |Yang Zhao |Hui Yang |Jingjing Zhao
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Aug 12, 2024 | 
nature.com | Hui Yang |Xiaojun Wang
AbstractUBE2M, a NEDD8-conjugating enzyme, is dysregulated in various human cancers and promotes tumor cell proliferation. However, its role in estrogen receptor-positive (ER+) breast cancer remains unknown. We found that UBE2M expression was significantly higher in ER+ breast cancer tissues than in ER-negative (ER-) breast cancer tissues. Higher expression of UBE2M indicated a poorer prognosis in patients with ER+ breast cancer but not in those with ER- breast cancer.
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Jun 14, 2024 | 
onlinelibrary.wiley.com | Yifan Wang |Hui Yang |Lili Wang |Chang Guo
1 Introduction Neuronal plasticity is a fundamental property of the nervous system that enables rapid adaptation in response to changes in an organism's internal and external environment.[1] This lifelong process mediates the structural and functional modifications of dendrites, axons, somata, and synapses and can be categorized into two types: synaptic and intrinsic.
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Apr 30, 2024 | 
springerprofessional.de | Hui Yang |Haitao Zhao
2024 | Buch This book describes the reliability research results and experience of BeiDou navigation satellite in engineering development.
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Apr 8, 2024 | 
pubs.acs.org | Yiwei Wu |Hui Yang |Qian He |He Jiang
Download Hi-Res ImageDownload to MS-PowerPointCite This:Nano Lett. 2024, XXXX, XXX Terms & Conditions Most electronic Supporting Information files are available without a subscription to ACS Web Editions. Such files may be downloaded by article for research use (if there is a public use license linked to the relevant article, that license may permit other uses).
