Huihui Fan

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Single-cell chromatin accessibility profiling of acute myeloid leukemia reveals heterogeneous lineage composition upon therapy-resistance - Communications Biology

Jul 21, 2023 | nature.com | Huihui Fan |Dapeng Hao |Fatima Zahra Jelloul |Ken Chen |Zhongming Zhao |Kunal Rai | +3 more

Human subjects and treatment regimenBone marrows from eight adult (>=18 years of age) patients on NCT02397720 protocol were included in this study. All patients had histologically proved relapsed or refractory acute myeloid leukemia. Timepoint A was collected at the time of proven relapse or primary refractoriness.

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