James Walshe

2 months ago | ejog.org | Maria Cheung |Patrick Williams |James Walshe |Karen Flood

We present a case report describing a rare cause of a common obstetric complication; pyloric web causing gross polyhydramnios. Polyhydramnios affects 1–2 % of pregnancies, and a proportion of these have an associated fetal anomaly that is not detectable antenatally. Pyloric webs are a rare cause of neonatal gastric outflow obstruction, however the exact incidence is unclear, and has been reported as less than 1 per million live births [ 1 2 ]. Treatment is by surgical excision.

Apr 3, 2024 | nature.com | Isaac Fianu |Moritz Ochmann |James Walshe |Olexandr Dybkov |Henning Urlaub

AbstractThe Integrator complex can terminate RNA polymerase II (Pol II) in the promoter-proximal region of genes. Previous work has shed light on how Integrator binds to the paused elongation complex consisting of Pol II, the DRB sensitivity-inducing factor (DSIF) and the negative elongation factor (NELF) and how it cleaves the nascent RNA transcript1, but has not explained how Integrator removes Pol II from the DNA template.

Sep 27, 2023 | mdpi.com | Kenneth Coldrick |James Walshe |Sarah McCormack |John Doran

3. Spectral Management of PV Systems As mentioned above, the loss mechanisms relating to the spectral management of a PV system are related to the limited spectral response from the solar-cell material [36].

Aug 29, 2023 | mdpi.com | Kenneth Coldrick |James Walshe |Sarah McCormack |John Doran

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