Jian Ge

Oct 10, 2024 | onlinelibrary.wiley.com | Dong Wang |Jian Ge |Yunze Zhao |Zishi Fang

CONFLICT OF INTEREST STATEMENT The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. Supporting Information Filename Description bjh19803-sup-0001-Supinfo.docxWord 2007 document , 1.7 MB Data S1. REFERENCES 1, . Hemophagocytic lymphohistiocytosis. Annu Rev Pathol. 2018; 13: 27–49. 2, . Pediatric hemophagocytic lymphohistiocytosis. Blood.

Aug 6, 2024 | biorxiv.org | Liuliu Yang |Tuo Zhang |Xue Dong |Jian Ge

AbstractThere is a paucity of human models to study immune-mediated host damage. Here, we utilized the GeoMx spatial multi-omics platform to analyze immune cell changes in COVID-19 pancreatic autopsy samples, revealing an accumulation of proinflammatory macrophages. Single cell RNA-seq analysis of human islets exposed to SARS-CoV-2 or Coxsackievirus B4 (CVB4) viruses identified activation of proinflammatory macrophages and β cell pyroptosis.

Dec 21, 2023 | pubs.rsc.org | Jian Ge |Jia Xu |Wen Chen

Preparation of microgels loaded with lycopene/ NMN and their protective mechanism of acute liver injury This study aimed to enhance the stability and bioavailability of lycopene (LYC) and nicotinamide mononucleotide (NMN) by incorporating them into porous microgels after loading LYC into liposomes.