Xue Dong

3 weeks ago | mdpi.com | Yang Liu |Xue Dong |Jian Shou Gao |Bowen Guan

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Oct 4, 2024 | mdpi.com | Zhiming Xin |Xing LI |Yonghua Li |Xue Dong

All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.

Aug 6, 2024 | biorxiv.org | Liuliu Yang |Tuo Zhang |Xue Dong |Jian Ge

AbstractThere is a paucity of human models to study immune-mediated host damage. Here, we utilized the GeoMx spatial multi-omics platform to analyze immune cell changes in COVID-19 pancreatic autopsy samples, revealing an accumulation of proinflammatory macrophages. Single cell RNA-seq analysis of human islets exposed to SARS-CoV-2 or Coxsackievirus B4 (CVB4) viruses identified activation of proinflammatory macrophages and β cell pyroptosis.

Jul 1, 2023 | pubs.acs.org | Xue Dong |Qingze Zeng |Li Dai |Xiang Ren

When consumed, excess progesterone (P4)─found in food and the environment─can lead to severe illnesses in humans. Therefore, quantitative analysis of P4 is critical for identifying its hazardous levels. In this study, a novel signal “on-amplified-off” P4 detection mode was proposed, which was based on the utilization of hafnium oxide (HfO2) as a unique electrochemiluminescence (ECL) emitter, produced by calcining UiO-66(Hf). This is the first time that HfO2 has been used as an ECL emitter.