Jiang Zhu

4 weeks ago | biorxiv.org | Jiang Zhu |Erik M Leith |Erin O'Donnell |Bryan P. Manzano

AbstractBRD4, a bromodomain and extraterminal (BET) family transcriptional regulator of cell cycle progression, cell differentiation and cancer development, is believed to be recruited to chromatin via interactions between its tandem bromodomains (BD1 and BD2) and acetylated histone tails.

Dec 6, 2024 | nature.com | Daniel J. Lunt |Jiang Zhu |Richard Wood

Current and future climate change is a major challenge facing humanity. Robustly constrained predictions of the impacts of future climate change, for a given scenario of anthropogenic carbon emissions, are needed to determine mitigation and adaptation strategies. Furthermore, calculating remaining carbon budgets to meet temperature targets is crucial for informing energy and economic policies.

Aug 6, 2024 | flipboard.com | Daniel J. Lunt |Bette L. Otto-Bliesner |Chris Brierley |Alan M. Haywood |Gordon Inglis |Kenji Izumi | +9 more

Paleoclimate data provide constraints on climate models' large-scale response to past CO2 changesThe paleoclimate record provides a test-bed in which climate models can be evaluated under conditions of substantial CO2 change; however, these data …

Jun 21, 2024 | medrxiv.org | Li Zhu |Jiang Zhu |Cheng-bo Li

The authors have declared no competing interest. The author(s) received no specific funding for this work. I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained.

Oct 20, 2023 | frontiersin.org | Aimin Jiang |Shibo Yu |Jiang Zhu |Shuang Wu

1 IntroductionOesophageal cancer (EC) is one of the most prevalent gastrointestinal malignant tumours, ranking eighth in worldwide tumour incidence and sixth in death (1). It is categorised into two mainr histological subtypes: oesophageal squamous cell carcinoma (ESCC) and oesophageal adenocarcinoma (EAC) (2).The most prevalent kind of EC, that take account over 90% of all EC occurrences, is ESCC.