Jianquan Liu

Aug 21, 2024 | nature.com | Qiang Lin |Jisen Zhang |Jianquan Liu

AbstractThe para rubber tree (Hevea brasiliensis) is the world’s sole commercial source of natural rubber, a vital industrial raw material. However, the narrow genetic diversity of this crop poses challenges for rubber breeding. Here, we generate high-quality de novo genome assemblies for three H. brasiliensis cultivars, two H. brasiliensis wild accessions, and three other Hevea species (H. nitida, H. pauciflora, and H. benthamiana).

Jul 1, 2024 | nature.com | Jianquan Liu

AbstractHelwingia, a shrub of the monotypic cosmopolitan family Helwingiaceae, is distinguished by its inflorescence, in which flowers are borne on the midrib of the leaf—a trait not commonly observed in related plant families. Previous studies have investigated the development of this unusual structure using comparative anatomical methods. However, the scarcity of genomic data has hindered our understanding of the origins and evolutionary history of this uncommon trait at the molecular level.

Mar 15, 2024 | molecular-cancer.biomedcentral.com | Tao Jiang |Junwen Qi |Zhenyu Xue |Bowen Liu |Jianquan Liu |Qihang hu | +7 more

ReferencesSiegel RL, Miller KD, Wagle NS, Jemal A. Cancer statistics, 2023. CA Cancer J Clin. 2023;73:17–48. PubMed  Google Scholar  Siegel RL, Wagle NS, Cercek A, Smith RA, Jemal A. Colorectal cancer statistics, 2023. CA Cancer J Clin. 2023;73:233–54. PubMed  Google Scholar  Andrei P, Battuello P, Grasso G, Rovera E, Tesio N, Bardelli A. Integrated approaches for precision oncology in colorectal cancer: the more you know, the better. Semin Cancer Biol. 2022;84:199–213.

Feb 2, 2024 | nature.com | Zeyu Zheng |Jianquan Liu

AbstractMerging structural variations (SVs) at the population level presents a significant challenge, yet it is essential for conducting comprehensive genotypic analyses, especially in the era of pangenomics. Here, we introduce PanPop, a tool that utilizes an advanced sequence-aware SV merging algorithm to efficiently merge SVs of various types. We demonstrate that PanPop can merge and optimize the majority of multiallelic SVs into informative biallelic variants.

Jun 1, 2023 | nature.com | Jianquan Liu

Author notesThese authors contributed equally: Donglei Wang, Yongshuai Sun, Weixiao Lei.