Jimin Pei

May 22, 2024 | onlinelibrary.wiley.com | Jimin Pei |Lisa N. Kinch |Qian Cong

1 INTRODUCTION A propeptide, also known as a proprotein, prosegment, prosequence, prodomain or pro region, is a specific segment of a protein's primary structure that is initially synthesized as part of the precursor protein but is later removed to generate the active or mature form.

Aug 25, 2023 | onlinelibrary.wiley.com | Jimin Pei |Qian Cong

Supporting Information Filename Description pro4764-sup-0001-Figures.pdfPDF document, 93.3 KB Supplementary Figure S1. The distribution of PAE values of AlphaFold models of human protein kinases. Supplementary Figure S2. The distribution of PAE values for KD-interacting residues predicted to be ordered and those predicted to be disordered.

Aug 12, 2023 | onlinelibrary.wiley.com | Kirill Medvedev |R. Schaeffer |Jimin Pei |Nick V. Grishin

Supporting Information Filename Description pro4750-sup-0001-FigureS1.pdfPDF document, 283.1 KB Figure S1. Missense mutations with benign clinical relevance mapped to kinase domain of Aurora kinase A (PDB: 3E5A). Color shows mutations frequency – from minimum (blue) to maximum (red) pro4750-sup-0002-TableS1.xlsxExcel 2007 spreadsheet , 24.2 KB Supplementary Table S1. Statistics for cancer and non-cancer mutations mapped to Aurora kinase A structure