Joanne C. Beer

Jun 11, 2024 | nature.com | Eliah G. Overbey |JangKeun Kim |Braden T. Tierney |Jiwoon Park |Deena Najjar |Remi Klotz | +30 more

AbstractSpaceflight induces molecular, cellular, and physiological shifts in astronauts and poses myriad biomedical challenges to the human body, which are becoming increasingly relevant as more humans venture into space1-6. Yet, current frameworks for aerospace medicine are nascent and lag far behind advancements in precision medicine on Earth, underscoring the need for rapid development of space medicine databases, tools, and protocols.

Dec 28, 2023 | mdpi.com | Joanne C. Beer |Kelly Lambert |Wai Feng Lim |Catherine Keane

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Nov 8, 2023 | nature.com | Joanne C. Beer |Alexandru Odainic |Jasper Spitzer |Dwight Kuo |Eicke Latz |Yuling Luo

AbstractThe blood proteome holds great promise for precision medicine but poses substantial challenges due to the low abundance of most plasma proteins and the vast dynamic range of the plasma proteome.

Oct 25, 2023 | biorxiv.org | Koji Abe |Joanne C. Beer |Tran Nguyen |Ishara S. Ariyapala

AbstractA variety of commercial platforms are available for the simultaneous detection of multiple cytokines and associated proteins, often employing antibody pairs to capture and detect target proteins. In this study, we comprehensively evaluated the performance of three distinct platforms: the fluorescent bead-based Luminex assay, the proximity extension-based Olink assay, and a novel proximity ligation assay platform known as Alamar NULISAseq.