John Andrews

1 month ago | biorxiv.org | Matthew Elliott |John Andrews |Jinghui Geng |Alex Spaeth

AbstractHow seizures begin at the level of microscopic neuronal circuits remains unknown. Advancements in high-density CMOS-based microelectrode arrays can be harnessed to study neuronal network activity with unprecedented spatial and temporal resolution. We use high-density electrophysiology recordings to probe the network activity of human hippocampal brain slices from six patients with mesial temporal lobe epilepsy.

Nov 25, 2024 | jamanetwork.com | John Andrews |Chris Mathews |Richard M. Schwartzstein |Sammer Marzouk

Graduate Medical Education, 2023-2024 The American Medical Association (AMA) and the Association of American Medical Colleges (AAMC) sponsor and administer the National GME (graduate medical education) Census through GME Track (an internet-based AAMC product). These organizations jointly maintain a database of information on training programs accredited by the Accreditation Council for Graduate Medical Education (ACGME) and of the residents and fellows enrolled in the programs.

Nov 25, 2024 | jamanetwork.com | John Andrews |Chris Mathews |Barbara Barzansky |Felicia Walker

Medical Education’s Learning Opportunity When I was studying at Johns Hopkins School of Public Health, I helped create an introduction to health policy class for public health and prehealth majors. That class is still taught today, some 25 years later, and I continue to lecture periodically about quality and access, the health care workforce, and other health care policy concerns.

Nov 25, 2024 | jamanetwork.com | Richard M. Schwartzstein |John Andrews |Chris Mathews |Barbara Barzansky

Gap Years—Unbridled Good or Unwarranted Cost? The medical school admissions process has become increasingly complex in recent years, with applicants seeking ways to strengthen their candidacy. One notable trend has been the increasing popularity of gap years, ie, years inserted between college and medical school to pursue additional experiences.

Nov 15, 2024 | nature.com | John Andrews |Kateryna Voitiuk |Alex Spaeth |Albert Wang |Jessica L. Sevetson |Kevin C. Donohue | +8 more

AbstractSeizures are made up of the coordinated activity of networks of neurons, suggesting that control of neurons in the pathologic circuits of epilepsy could allow for control of the disease. Optogenetics has been effective at stopping seizure-like activity in non-human disease models by increasing inhibitory tone or decreasing excitation, although this effect has not been shown in human brain tissue.