John W. Tobias

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James Remar Net Worth

Jun 24, 2024 | celebritynetworth.com | John W. Tobias

Category:Richest Celebrities › ActorsNet Worth:$2.5 MillionBirthdate:Dec 31, 1953 (70 years old)Birthplace:BostonGender:MaleHeight:5 ft 10 in (1.79 m)Profession:Actor, Voice ActorNationality:United States of America 💰 Compare James Remar's Net Worth What is James Remar's Net Worth? James Remar is an American actor who has a net worth of $2.5 million.
Plasticity-induced repression of Irf6 underlies acquired resistance to cancer immunotherapy in pancreatic ductal adenocarcinoma - Nature Communications

Feb 20, 2024 | nature.com | Il-Kyu Kim |Jeffrey Lin |Stacy Thomas |Takeshi Katsuda |John W. Tobias |Robert H Vonderheide

AbstractAcquired resistance to immunotherapy remains a critical yet incompletely understood biological mechanism. Here, using a mouse model of pancreatic ductal adenocarcinoma (PDAC) to study tumor relapse following immunotherapy-induced responses, we find that resistance is reproducibly associated with an epithelial-to-mesenchymal transition (EMT), with EMT-transcription factors ZEB1 and SNAIL functioning as master genetic and epigenetic regulators of this effect.

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