Jouke-Jan Hottenga

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Genome-Wide Association Study of Obsessive-Compulsive Symptoms including 33,943 individuals from the general population - Molecular Psychiatry

Mar 27, 2024 | nature.com | Nora I. Strom |Christie L. Burton |René Pool |James J. Crowley |Jouke-Jan Hottenga |Henrik R. Larsson | +6 more

AbstractWhile 1–2% of individuals meet the criteria for a clinical diagnosis of obsessive-compulsive disorder (OCD), many more (~13–38%) experience subclinical obsessive-compulsive symptoms (OCS) during their life.
Genomics Research of Lifetime Depression in the Netherlands: The BIObanks Netherlands Internet Collaboration (BIONIC) Project

Mar 18, 2024 | cambridge.org | Yuri Milaneschi |Jouke-Jan Hottenga |Mariska Bot |Floris Huider

Major depressive disorder (MDD) is a mental health condition characterized by decreased mood and anhedonia that severely impacts quality of life. It affects up to 20% of the population across the lifetime and is a leading contributor to disability worldwide (Kessler & Bromet, Reference Kessler and Bromet2013; Marx et al., Reference Marx, Penninx, Solmi, Furukawa, Firth, Carvalho and Berk2023; World Health Organization [WHO], 2017).

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