Jun L Zhou

Oct 18, 2024 | nature.com | Zihao Wang |Qian Zhang |Jun L Zhou

AbstractMorphogens play a critical role in coordinating stress adaptation and aging across tissues, yet their involvement in neuronal mitochondrial stress responses and systemic effects remains unclear. In this study, we reveal that the transforming growth factor beta (TGF-β) DAF-7 is pivotal in mediating the intestinal mitochondrial unfolded protein response (UPRmt) in Caenorhabditis elegans under neuronal mitochondrial stress.

Sep 4, 2024 | nature.com | Jun L Zhou

AbstractDefects in meiotic prophase can cause meiotic chromosome missegregation and aneuploid gamete formation. Meiotic checkpoints are activated in germ cells with meiotic defects, and cells with unfixed errors are eliminated by apoptosis. How such a surveillance process is regulated remains elusive. Here, we report that a chromosome-coupled ubiquitin-proteasome pathway (UPP) regulates meiotic checkpoint activation and promotes germ cell apoptosis in C. elegans meiosis-defective mutants.

Sep 3, 2024 | nature.com | Xue Liu |Jun L Zhou

AbstractLettuce (Lactuca sativa L., Asteraceae) is one of the most important vegetable crops, known for its various horticultural types and significant morphological variation. The first reference genome of lettuce, a crisphead type (L. sativa var. capitata cv. Salinas), was previously released. Here, we reported a near-complete chromosome-level reference genome for looseleaf lettuce (L. sativa var. crispa).

Sep 18, 2023 | pubs.rsc.org | Jun L Zhou |Chengyue Zou |Chengxiang Chu |Shasha Liu

Synthesis of N, Si co-doped carbon dots to establish fluorescent sensor for Hg(II) detection with triple signal outp Mercury is deemed as the heavy metal with extreme toxicity. Thus it is of significance to develop effective method for mercury ions detection with high performances. In the work, carbon dots doped with nitrogen and silicon (N, Si/CQDs) was successfully prepared from folic acid and N-[3-(trimethoxysily)propyl]-ethylenediamine.

Sep 8, 2023 | mdpi.com | Jun L Zhou |Chunbo Zhang |Wu Liang |Yanquan Wu

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