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1 week ago | 
nature.com | Jun Lyu
The researchers sequenced a panel of 226 citrus accessions including sour oranges, landraces and cultivated citrus, and integrated published genomes of sweet orange, pummelo and mandarin in their analyses. Unlike sweet oranges, sour oranges exhibited high genetic and metabolic diversity and high variation in susceptibility to citrus canker. Shared heterozygous genomic segments between sour and sweet oranges traced their common parentage to mandarin and pummelo lineages.
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1 month ago | 
nature.com | Jun Lyu
Phosphate deficiency promotes SL biosynthesis and secretion into soil. Using a hydroponic sorghum growth system that enables convenient manipulation of phosphate conditions, the researchers observed upregulation of genes for SL biosynthesis and signalling, and ABC transporters, under conditions of phosphate deficiency.
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1 month ago | 
biorxiv.org | Jun Lyu |Xiaoyan Xu |Chongyi Chen
AbstractSequencing newly synthesized transcriptome alongside regular transcriptome in single cells enables the study of gene expression temporal dynamics during rapid chromatin and gene regulation processes. Existing assays for profiling single-cell newly synthesized transcriptome often require specialized technical expertise to achieve high cellular throughput, limiting their accessibility.
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Jan 1, 2025 | 
nature.com | Jun Lyu
Progress in sequencing technology has made the pangenomes of many species available, which has improved our understanding of natural variations and the evolution of species (M. Schreiber et al. Nat. Rev. Genet. 25, 563–577; 2024). In a recent issue of Nature, Chengzhi Jiao from the Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, and colleagues reported genome assemblies for 17 wheat cultivars released in China in different periods since the 1950s.
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Dec 30, 2024 | 
alzres.biomedcentral.com | Shiqi Yuan |Qing Liu |Xiaxuan Huang |Zihong Bai |Juan Yu |Huan Le | +7 more
The UK Biobank is a large-scale, population-based prospective study designed to comprehensively investigate the genetic and non-genetic determinants of disease in middle-aged and older individuals. Its objective is to combine broad and precise exposure assessments with detailed tracking and characterization of numerous health-related outcomes, aiming to contribute to the development of innovative scientific knowledge by optimizing resource utilization.
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Dec 3, 2024 | 
nature.com | Jun Lyu
Using recombinant inbred lines developed by crossing two maize inbred lines with different KDRs, the researchers identified a large-effect quantitative trait locus, qKDR1. A 1,417-bp sequence of this locus is causal because its knockout slows KDR. Different alleles at this locus correspond to different KDRs and differential expression of a nearby RPG (qKDR1 REGULATED PEPTIDE GENE) gene.
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Nov 29, 2024 | 
mdpi.com | Jun Lyu |Chongyi Chen
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Nov 6, 2024 | 
nature.com | Jun Lyu
Many LACs are regulated by copper-miRNAs (Cu-miRNAs), which target genes encoding copper-containing proteins. LACs are required for lignification and flavonoid synthesis in plants and have been associated with plant development and stress tolerance. So, the researchers investigated the effects on stress tolerance of manipulating Cu-miRNAs. Specifically, they chose three Cu-miRNAs (miR397, miR408 and miR528), as these three collectively target 18 out of the 28 LAC family genes in rice.
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Oct 9, 2024 | 
nature.com | Jun Lyu
The rationale of CEST is to transfer magnetization from low-concentration metabolites to highly concentrated water molecules using proton exchange, so that the saturation effects of metabolites can be effectively amplified and observed in water. The researchers used CEST to image metabolites in living plants, with a focus on saccharides and amino acids. They first applied CEST to visualize sugars and amino acids in the endosperm of pea seeds using chemical shift imaging (CSI) as a control.
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Sep 3, 2024 | 
nature.com | Jun Lyu
They first performed chloroplast sequencing on 36 wild and 77 cultivated accessions and whole-genome sequencing on a larger panel of 367 accessions (including 353 A. hypogaea, 2 A. monticola, 11 A. duranensis and 1 A. ipaensis). The diploid species A. duranensis and A. ipaensis have been considered to contribute to the A and B subgenomes of A. hypogaea, respectively, and A. hypogaea includes two subspecies (A. hypogaea subsp. hypogaea (Ahh) and A. hypogaea subsp. fastigiata (Ahf)).
